Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein (Q37110710)

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scientific article published on 24 December 2008

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English	Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein	scientific article published on 24 December 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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3

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M Essex

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Christian L Boutwell

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Christopher F Rowley

2

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Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

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publication date

24 December 2008

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Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Virology

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Europe PubMed Central

PMC publication ID

18 August 2017

83

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Europe PubMed Central

PMC publication ID

18 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

2460-2468

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648284

14 September 2017

Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648284

14 September 2017

Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss

1 reference

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14 September 2017

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection

1 reference

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14 September 2017

Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture

1 reference

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14 September 2017

Maintenance of viral suppression in HIV-1-infected HLA-B*57+ elite suppressors despite CTL escape mutations

1 reference

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14 September 2017

Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1

1 reference

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14 September 2017

Rapid viral escape at an immunodominant simian-human immunodeficiency virus cytotoxic T-lymphocyte epitope exacts a dramatic fitness cost

1 reference

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14 September 2017

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.

1 reference

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14 September 2017

Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope

1 reference

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14 September 2017

Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child

1 reference

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14 September 2017

Structural constraints on viral escape from HIV- and SIV-specific cytotoxic T-lymphocytes

1 reference

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Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial

1 reference

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14 September 2017

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

1 reference

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14 September 2017

Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20).

1 reference

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14 September 2017

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

1 reference

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14 September 2017

Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response

1 reference

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14 September 2017

Simian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope.

1 reference

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14 September 2017

Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual

1 reference

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14 September 2017

Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys

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Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes

1 reference

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14 September 2017

Implications of antiretroviral resistance on viral fitness

1 reference

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14 September 2017

Construction and analysis of an infectious human Immunodeficiency virus type 1 subtype C molecular clone

1 reference

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14 September 2017

Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.

1 reference

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14 September 2017

A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression

1 reference

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14 September 2017

Definition of five new simian immunodeficiency virus cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I molecules: evidence for an influence on disease progression.

1 reference

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HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

1 reference

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Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.

1 reference

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Lack of strong immune selection pressure by the immunodominant, HLA-A*0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection

1 reference

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Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

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14 September 2017

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

1 reference

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Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

1 reference

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14 September 2017

Use of a novel assay based on intact recombinant viruses expressing green (EGFP) or red (DsRed2) fluorescent proteins to examine the contribution of pol and env genes to overall HIV-1 replicative fitness

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Altered HIV-1 Gag protein interactions with cyclophilin A (CypA) on the acquisition of H219Q and H219P substitutions in the CypA binding loop

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Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors

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Evolution of HIV-1 in an HLA-B*57-positive patient during virologic escape.

1 reference

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HIV evolution: CTL escape mutation and reversion after transmission

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Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection

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Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia.

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Antagonism of cytotoxic T lymphocyte-mediated lysis by natural HIV-1 altered peptide ligands requires simultaneous presentation of agonist and antagonist peptides.

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Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection

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Reversion of CTL escape–variant immunodeficiency viruses in vivo

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CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individuals

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Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

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Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression

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https://pubmed.ncbi.nlm.nih.gov/19109381

12 December 2020

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Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/19109381

12 December 2020

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Effectiveness of 3TC in HIV clinical trials may be due in part to the M184V substitution in 3TC-resistant HIV-1 reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19109381

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based on heuristic

inferred from PubMed ID database lookup

HLA and AIDS: a cautionary tale

1 reference

https://pubmed.ncbi.nlm.nih.gov/19109381

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01970-08

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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