Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy. (Q37103998)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23901116%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy (English)

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6 March 2020

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6 March 2020

Thomas A Cooper

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6 March 2020

language of work or name

English

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publication date

30 July 2013

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Proceedings of the National Academy of Sciences of the United States of America

6 March 2020

published in

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6 March 2020

volume

110

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6 March 2020

issue

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6 March 2020

page(s)

13570-13575

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ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

6 March 2020

cites work

1 reference

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GSK3β mediates muscle pathology in myotonic dystrophy

14 September 2017

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Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides

14 September 2017

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The myotonic dystrophies: molecular, clinical, and therapeutic challenges

14 September 2017

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14 September 2017

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PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis

14 September 2017

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Emerging roles of PKM2 in cell metabolism and cancer progression

14 September 2017

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Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

14 September 2017

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Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel

14 September 2017

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Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons

14 September 2017

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Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

14 September 2017

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Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

14 September 2017

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Alternative splicing dysregulation secondary to skeletal muscle regeneration

14 September 2017

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CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1.

14 September 2017

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The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

14 September 2017

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Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy.

14 September 2017

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Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1.

14 September 2017

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Mice deficient in ribosomal protein S6 phosphorylation suffer from muscle weakness that reflects a growth defect and energy deficit

14 September 2017

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Vivo-Morpholinos: a non-peptide transporter delivers Morpholinos into a wide array of mouse tissues

14 September 2017

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

14 September 2017

1 reference

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Pyruvate kinase M2 is a phosphotyrosine-binding protein

14 September 2017

1 reference

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Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation

14 September 2017

1 reference

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Myotonic dystrophy: RNA-mediated muscle disease

14 September 2017

1 reference

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Molecular mechanisms responsible for aberrant splicing of SERCA1 in myotonic dystrophy type 1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746907

A muscleblind knockout model for myotonic dystrophy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746907

High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746907

Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746907

Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7.

14 September 2017

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Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9

14 September 2017

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Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy

14 September 2017

1 reference

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The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746907

Myotonic dystrophy mutation: an unstable CTG repeat in the 3' untranslated region of the gene

14 September 2017

1 reference

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Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member.

14 September 2017

1 reference

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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

14 September 2017

1 reference

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Multimolecular forms of pyruvate kinase from rat and other mammalian tissues. I. Electrophoretic studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746907

Mechanism of muscle wasting in myotonic dystrophy

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746907

Codon optimization markedly improves doxycycline regulated gene expression in the mouse heart

27 June 2018

1 reference

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Lactate dehydrogenase in lung cancer

3 September 2018

1 reference

12 December 2020

Temporally distinctive changes of alternative splicing patterns during myogenic differentiation of C2C12 cells

1 reference

12 December 2020

Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy

1 reference

12 December 2020

Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2

1 reference

12 December 2020

In vivo estimation of muscle protein synthesis in myotonic dystrophy

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1308806110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23901116%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

0 references

1 reference

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6 March 2020

PubMed publication ID

23901116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23901116%20AND%20SRC:MED&resulttype=core&format=json