Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development (Q37109508)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438701%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development (English)

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9 November 2019

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9 November 2019

1 reference

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9 November 2019

J Y Choi

1 reference

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9 November 2019

J Pratap

1 reference

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9 November 2019

L Xing

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9 November 2019

E Balint

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9 November 2019

S Dalamangas

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9 November 2019

B Boyce

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9 November 2019

A J van Wijnen

1 reference

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9 November 2019

J B Lian

1 reference

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9 November 2019

J L Stein

1 reference

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9 November 2019

S N Jones

1 reference

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9 November 2019

G S Stein

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9 November 2019

language of work or name

English

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publication date

3 July 2001

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Proceedings of the National Academy of Sciences of the United States of America

9 November 2019

published in

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9 November 2019

volume

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9 November 2019

issue

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9 November 2019

page(s)

8650-8655

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Alterations in subnuclear trafficking of nuclear regulatory factors in acute leukemia

9 November 2019

cites work

1 reference

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runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins

14 September 2017

1 reference

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Experimental observations of a nuclear matrix

14 September 2017

1 reference

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A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

14 September 2017

1 reference

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Groucho/TLE family proteins and transcriptional repression

14 September 2017

1 reference

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Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription

14 September 2017

1 reference

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Nuclear structure-gene expression interrelationships: implications for aberrant gene expression in cancer

14 September 2017

1 reference

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Dynamics of DNA replication factories in living cells

14 September 2017

1 reference

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Smads as transcriptional co-modulators

14 September 2017

1 reference

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The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

14 September 2017

1 reference

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Mammalian runt-domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia

14 September 2017

1 reference

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Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF.

14 September 2017

1 reference

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The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor

14 September 2017

1 reference

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Biological characteristics of the leukemia-associated transcriptional factor AML1 disclosed by hematopoietic rescue of AML1-deficient embryonic stem cells by using a knock-in strategy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Cbfa1 isoform overexpression upregulates osteocalcin gene expression in non-osteoblastic and pre-osteoblastic cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

The organization of replication and transcription

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Maturational disturbance of chondrocytes in Cbfa1-deficient mice

14 September 2017

1 reference

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Core-binding factor: a central player in hematopoiesis and leukemia

14 September 2017

1 reference

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Regulation of chondrocyte differentiation by Cbfa1

14 September 2017

1 reference

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Cbfa1 isoforms exert functional differences in osteoblast differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Structure and Function in the Nucleus

14 September 2017

2 references

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14 September 2017

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Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains

21 January 2018

1 reference

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Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

14 September 2017

1 reference

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Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex

14 September 2017

1 reference

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Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

14 September 2017

1 reference

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Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Osteocalcin gene promoter-binding factors are tissue-specific nuclear matrix components

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Association of nuclear matrix antigens with exon-containing splicing complexes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Rethinking cell structure

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: interactions with the osteocalcin gene promoter

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Chromosome engineering in mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Cbfa1, an essential transcription factor for bone formation, is expressed in testis from the same promoter used in bone

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Segregation of transcription and replication sites into higher order domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

AML-2 is a potential target for transcriptional regulation by the t(8;21) and t(12;21) fusion proteins in acute leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Domains of the human androgen receptor and glucocorticoid receptor involved in binding to the nuclear matrix

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

29 September 2017

1 reference

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DNase I hypersensitive sites in promoter elements associated with basal and vitamin D dependent transcription of the bone-specific osteocalcin gene

27 June 2018

1 reference

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Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=37490

Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene

27 June 2018

1 reference

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RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo

27 June 2018

1 reference

12 December 2020

Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2

1 reference

12 December 2020

Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1

1 reference

12 December 2020

Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies

1 reference

12 December 2020

A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene

1 reference

12 December 2020

Functional dissection of the alpha and beta subunits of transcription factor PEBP2 and the redox susceptibility of its DNA binding activity

1 reference

12 December 2020

Structural analysis and characterization of tissue and hormonal responsive expression of the avian bone sialoprotein (BSP) gene

1 reference

12 December 2020

CBFa(AML/PEBP2)-related elements in the TGF-beta type I receptor promoter and expression with osteoblast differentiation

1 reference

12 December 2020

The DNA-binding and tau2 transactivation domains of the rat glucocorticoid receptor constitute a nuclear matrix-targeting signal

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.151236498

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438701%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438701%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

11438701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438701%20AND%20SRC:MED&resulttype=core&format=json