Synthesis of macrocyclic trypanosomal cysteine protease inhibitors (Q37097725)

18 August 2017

Synthesis of macrocyclic trypanosomal cysteine protease inhibitors (English)

1 reference

18 August 2017

James H McKerrow

1 reference

18 August 2017

Yen Ting Chen

1 reference

18 August 2017

Ricardo Lira

series ordinal

1 reference

18 August 2017

Elizabeth Hansell

series ordinal

1 reference

18 August 2017

William R Roush

series ordinal

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18 August 2017

language of work or name

English

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publication date

10 June 2008

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Bioorganic & Medicinal Chemistry Letters

18 August 2017

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inferred from page(s)

published in

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18 August 2017

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18 August 2017

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18 August 2017

5860-5863

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Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis)

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Progresses in the field of drug design to combat tropical protozoan parasitic diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

A cysteine protease inhibitor protects dogs from cardiac damage during infection by Trypanosoma cruzi.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Irreversible inhibitors of serine, cysteine, and threonine proteases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Recent advances in the synthesis, design and selection of cysteine protease inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Synthesis and activity of a new generation of ruthenium-based olefin metathesis catalysts coordinated with 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ligands

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

The proteases and pathogenicity of parasitic protozoa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Chemotherapy of parasitic infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Potency and selectivity of P2/P3-modified inhibitors of cysteine proteases from trypanosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Macrocyclization in the design of a conformationally constrained Grb2 SH2 domain inhibitor

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Production of crystallizable cruzain, the major cysteine protease from Trypanosoma cruzi

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

The crystal structure of cruzain: a therapeutic target for Chagas' disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Synthesis of acyclic and dehydroaspartic acid analogues of Ac-Asp-Glu-OH and their inhibition of rat brain N-acetylated alpha-linked acidic dipeptidase (NAALA dipeptidase).

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642929

Structure-activity relationships for inhibition of papain by peptide Michael acceptors

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18585034

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18585034

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cyclic phosphopeptides for interference with Grb2 SH2 domain signal transduction prepared by ring-closing metathesis and phosphorylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18585034

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2008.06.012

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

18585034

1 reference