Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release (Q37071048)

18 August 2017

Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release (English)

1 reference

18 August 2017

1 reference

Josep Rizo

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18 August 2017

Cong Ma

1 reference

18 August 2017

Lijing Su

series ordinal

1 reference

18 August 2017

Alpay B Seven

series ordinal

1 reference

18 August 2017

Yibin Xu

series ordinal

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18 August 2017

language of work or name

English

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publication date

20 December 2012

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18 August 2017

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18 August 2017

339

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18 August 2017

6118

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18 August 2017

421-425

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Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

The Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering Factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Membrane fusion: grappling with SNARE and SM proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

The Janus-faced nature of the C(2)B domain is fundamental for synaptotagmin-1 function.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

29 September 2017

Synaptic vesicle fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Munc18-1 binds directly to the neuronal SNARE complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Presynaptic calcium and control of vesicle fusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Synaptotagmin I functions as a calcium regulator of release probability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

SNAREpins are functionally resistant to disruption by NSF and alphaSNAP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Synaptic assembly of the brain in the absence of neurotransmitter secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

A conformational switch in syntaxin during exocytosis: role of munc18.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

SNAREpins: minimal machinery for membrane fusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Selective activation of cognate SNAREpins by Sec1/Munc18 proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Remote homology between Munc13 MUN domain and vesicle tethering complexes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

A minimal domain responsible for Munc13 activity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

UNC-13 is required for synaptic vesicle fusion in C. elegans

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

The synaptic SNARE complex is a parallel four-stranded helical bundle

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3733786

Three-dimensional structure of the complexin/SNARE complex

4 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

SNARE-mediated lipid mixing depends on the physical state of the vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Binding of Munc18-1 to synaptobrevin and to the SNARE four-helix bundle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Line narrowing in methyl-TROSY using zero-quantum 1H-13C NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Arachidonic acid allows SNARE complex formation in the presence of Munc18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Membrane Bridging and Hemifusion by Denaturated Munc18

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Neuronal SNAREs do not trigger fusion between synthetic membranes but do promote PEG-mediated membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

A single-vesicle content mixing assay for SNARE-mediated membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Membrane fusion catalyzed by a Rab, SNAREs, and SNARE chaperones is accompanied by enhanced permeability to small molecules and by lysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Structural Changes Are Associated with SolubleN-Ethylmaleimide-sensitive Fusion Protein Attachment Protein Receptor Complex Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

SNAREs--engines for membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Self-association of the H3 region of syntaxin 1A. Implications for intermediates in SNARE complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

The four-helix bundle of the neuronal target membrane SNARE complex is neither disordered in the middle nor uncoiled at the C-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Vam3p structure reveals conserved and divergent properties of syntaxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

Sec1p binds to SNARE complexes and concentrates at sites of secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1230473

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1230473

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

23258414

1 reference