Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization. (Q37047327)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

0 references

1 reference

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13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Joanne H Reed

1 reference

17 August 2017

Jennifer Jackson

series ordinal

1 reference

17 August 2017

Daniel Christ

series ordinal

1 reference

17 August 2017

Christopher C Goodnow

series ordinal

1 reference

17 August 2017

language of work or name

English

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publication date

13 June 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

13 March 2020

published in

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13 March 2020

volume

213

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13 March 2020

issue

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13 March 2020

page(s)

1255-1265

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The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains.

13 March 2020

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Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.

29 September 2017

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A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

29 September 2017

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Human immunoglobulin selection associated with class switch and possible tolerogenic origins for C delta class-switched B cells

29 September 2017

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29 September 2017

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29 September 2017

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Evidence for involvement of a hydrophobic patch in framework region 1 of human V4-34-encoded Igs in recognition of the red blood cell I antigen

29 September 2017

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29 September 2017

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Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance

29 September 2017

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Three-dimensional structure of the Fab from a human IgM cold agglutinin

29 September 2017

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Relative roles of somatic and Darwinian evolution in shaping the antibody response

29 September 2017

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29 September 2017

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Receptor editing: an approach by autoreactive B cells to escape tolerance

29 September 2017

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29 September 2017

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29 September 2017

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Clonal anergy: persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen

29 September 2017

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Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype

29 September 2017

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Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift

29 September 2017

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29 September 2017

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29 September 2017

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27 June 2018

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27 June 2018

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Human monoclonal antibodies against blood group antigens preferentially express a VH4-21 variable region gene-associated epitope

27 June 2018

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Variable region gene analysis of pathologic human autoantibodies to the related i and I red blood cell antigens

27 June 2018

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An anti-B cell autoantibody from Wiskott-Aldrich syndrome which recognizes i blood group specificity on normal human B cells

27 June 2018

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The inference of phased haplotypes for the immunoglobulin H chain V region gene loci by analysis of VDJ gene rearrangements.

27 June 2018

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Lupus IgG VH4.34 antibodies bind to a 220-kDa glycoform of CD45/B220 on the surface of human B lymphocytes

4 September 2018

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Tracking of the V4-34 (VH4-21) gene in human tonsil reveals clonal isotype switch events and a highly variable degree of somatic hypermutation

4 September 2018

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Breakdown of self-tolerance in anergic B lymphocytes.

4 September 2018

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A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

4 September 2018

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21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.20151978

Contribution of Receptor Editing to the Antibody Repertoire

21 January 2018

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21 January 2018

12 December 2020

Evidence for the occurrence of O-glycosidically linked oligosaccharides of poly-N-acetyllactosamine type on the human leucocyte common antigen

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Induction of self-tolerance in mature peripheral B lymphocytes

21 January 2018

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The antibody response: a model based on antagonistic actions of antigen

21 January 2018

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12 December 2020

TOLERANCE TO A PROTEIN ANTIGEN IN ADULT MICE AND THE EFFECT OF NONSPECIFIC FACTORS

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IMGT/V-QUEST: IMGT Standardized Analysis of the Immunoglobulin (IG) and T Cell Receptor (TR) Nucleotide Sequences

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The I Binding Specificity of Human VH4-34 (VH4-21) Encoded Antibodies is Determined by Both VHFramework Region 1 and Complementarity Determining Region 3

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12 December 2020

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

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Autoanti-red cell antibodies synthesized by patients with infectious mononucleosis utilize the VH4-21 gene segment

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12 December 2020

Identifiers

DOI

10.1084/JEM.20151978

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

27298445

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27298445%20AND%20SRC:MED&resulttype=core&format=json