BET proteins promote efficient murine leukemia virus integration at transcription start sites (Q37031911)

17 August 2017

BET proteins promote efficient murine leukemia virus integration at transcription start sites (English)

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17 August 2017

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murine leukemia virus

object named as

murine leukemia virus

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Elizabeth Coward

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Li Wu

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Frederic D Bushman

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Mamuka Kvaratskhelia

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17 August 2017

Amit Sharma

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17 August 2017

Ross C Larue

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17 August 2017

Matthew R Plumb

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17 August 2017

Nirav Malani

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17 August 2017

Frances Male

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17 August 2017

Alison Slaughter

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17 August 2017

Jacques J Kessl

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17 August 2017

Nikolozi Shkriabai

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17 August 2017

Sriram S Aiyer

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17 August 2017

Patrick L Green

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17 August 2017

Monica J Roth

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17 August 2017

language of work or name

English

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publication date

1 July 2013

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Proceedings of the National Academy of Sciences of the United States of America

17 August 2017

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17 August 2017

110

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17 August 2017

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17 August 2017

12036-12041

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3718171/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins.

9 September 2017

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Comparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses

9 September 2017

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BET domain co-regulators in obesity, inflammation and cancer

9 September 2017

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Gene therapy for primary immunodeficiencies

9 September 2017

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Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing

9 September 2017

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MuLV IN mutants responsive to HDAC inhibitors enhance transcription from unintegrated retroviral DNA.

9 September 2017

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Bromodomain protein Brd4 associated with acetylated chromatin is important for maintenance of higher-order chromatin structure

9 September 2017

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Gene therapy for primary adaptive immune deficiencies

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HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2

9 September 2017

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Selective inhibition of BET bromodomains

9 September 2017

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Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration

9 September 2017

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Retroviral intasome assembly and inhibition of DNA strand transfer

9 September 2017

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9 September 2017

WHAT do viruses BET on?

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Integration target site selection by a resurrected human endogenous retrovirus

9 September 2017

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Dynamic modulation of HIV-1 integrase structure and function by cellular lens epithelium-derived growth factor (LEDGF) protein

9 September 2017

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Host proteins interacting with the Moloney murine leukemia virus integrase: multiple transcriptional regulators and chromatin binding factors

9 September 2017

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Retrotransposon Tf1 is targeted to Pol II promoters by transcription activators.

9 September 2017

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The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

9 September 2017

1 reference

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LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

9 September 2017

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The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

9 September 2017

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Selection of target sites for mobile DNA integration in the human genome

9 September 2017

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Development of hematopoietic stem cell gene therapy for Wiskott-Aldrich syndrome.

9 September 2017

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An essential role for LEDGF/p75 in HIV integration

9 September 2017

1 reference

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Retroviral DNA integration: viral and cellular determinants of target-site selection

9 September 2017

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Retroviral DNA integration: HIV and the role of LEDGF/p75.

9 September 2017

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Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.

9 September 2017

1 reference

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Interaction of bovine papillomavirus E2 protein with Brd4 stabilizes its association with chromatin

9 September 2017

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The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding

9 September 2017

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Brd4: tethering, segregation and beyond

9 September 2017

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Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

9 September 2017

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Selective recognition of acetylated histones by bromodomain proteins visualized in living cells

9 September 2017

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Transcription start regions in the human genome are favored targets for MLV integration

9 September 2017

1 reference

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Controlling integration specificity of a yeast retrotransposon

9 September 2017

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HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

9 September 2017

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HIV-1 integration in the human genome favors active genes and local hotspots

9 September 2017

1 reference

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Assembly and catalysis of concerted two-end integration events by Moloney murine leukemia virus integrase

9 September 2017

1 reference

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The bromodomain: a chromatin-targeting module?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718171

Reactivation of latent HIV-1 by inhibition of BRD4.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718171

LEDGF (p75) promotes DNA-end resection and homologous recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718171

A role for LEDGF/p75 in targeting HIV DNA integration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718171

Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718171

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718171

Gammaretroviral integration into nucleosomal target DNA in vivo

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718171

TFIIIB subunit Bdp1p is required for periodic integration of the Ty1 retrotransposon and targeting of Isw2p to S. cerevisiae tDNAs

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718171

27 June 2018

Identifiers

DOI

10.1073/PNAS.1307157110

1 reference

17 August 2017

0 references

1 reference

17 August 2017

PubMed publication ID

23818621

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