Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes (Q36979395)

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scientific article published on 23 April 2008

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English	Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes	scientific article published on 23 April 2008

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instance of

scholarly article

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Europe PubMed Central

PMC publication ID

2585649

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17 August 2017

title

Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes (English)

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Europe PubMed Central

PMC publication ID

2585649

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17 August 2017

main subject

DNA damage

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Alzheimer's disease

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astrocyte

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phosphorylation

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based on heuristic

inferred from title

author

George Perry

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7

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Europe PubMed Central

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2585649

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17 August 2017

Xiongwei Zhu

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2

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Xiongwei Zhu

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PMC publication ID

2585649

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17 August 2017

Mark Anthony Smith

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8

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Mark A Smith

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Europe PubMed Central

PMC publication ID

2585649

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17 August 2017

Sandra L Siedlak

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Sandra L Siedlak

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2585649

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17 August 2017

Hyoung-gon Lee

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9

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Hyoung-gon Lee

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Europe PubMed Central

PMC publication ID

2585649

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17 August 2017

Rudy J Castellani

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4

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Rudy J Castellani

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2585649

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17 August 2017

author name string

Na-Hye Myung

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1

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2585649

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17 August 2017

Inna I Kruman

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3

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2585649

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17 August 2017

Robert B Petersen

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5

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Europe PubMed Central

PMC publication ID

2585649

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17 August 2017

publication date

23 April 2008

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Europe PubMed Central

PMC publication ID

2585649

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17 August 2017

published in

Age

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Europe PubMed Central

PMC publication ID

2585649

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17 August 2017

volume

30

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Europe PubMed Central

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2585649

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17 August 2017

issue

4

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Europe PubMed Central

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2585649

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17 August 2017

page(s)

209-215

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17 August 2017

cites work

Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents

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PubMed Central

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29 September 2017

DNA damage checkpoints: from initiation to recovery or adaptation

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29 September 2017

Apoptosis in Alzheimer disease: a mathematical improbability

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29 September 2017

Defense mechanism to oxidative DNA damage in glial cells

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Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease

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29 September 2017

Histone H2AX in DNA damage and repair.

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29 September 2017

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

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29 September 2017

Signaling to chromatin through histone modifications

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29 September 2017

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

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PubMed Central

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29 September 2017

Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

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29 September 2017

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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29 September 2017

Effect of Postmortem Interval on In Situ End-Labeling of DNA Oligonucleosomes

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The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

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29 September 2017

DNA damage and activated caspase-3 expression in neurons and astrocytes: evidence for apoptosis in frontotemporal dementia

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Signal transduction abnormalities in Alzheimer's disease: evidence of a pathogenic stimuli

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Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

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Essential protective roles of reactive astrocytes in traumatic brain injury

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Increased TUNEL positive cells in human alcoholic brains

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Increased p27, an essential component of cell cycle control, in Alzheimer's disease

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4 September 2018

Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?

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4 September 2018

Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle.

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4 September 2018

Apoptosis of astrocytes with enhanced lysosomal activity and oligodendrocytes in white matter lesions in Alzheimer's disease

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4 September 2018

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

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4 September 2018

Abortive apoptosis in Alzheimer's disease

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4 September 2018

Astrocytes degenerate in frontotemporal dementia: possible relation to hypoperfusion

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4 September 2018

Neuronal polo-like kinase in Alzheimer disease indicates cell cycle changes

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4 September 2018

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DNA damage distribution in the human brain as shown by in situ end labeling; area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology.

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4 September 2018

c-Jun, JNK/SAPK kinases and transcription factor NF-kappa B are selectively activated in astrocytes, but not motor neurons, in amyotrophic lateral sclerosis

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Involvement of histone phosphorylation in apoptosis of human astrocytes after exposure to saline solution

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https://pubmed.ncbi.nlm.nih.gov/19424844

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DNA damage response: determining the fate of phosphorylated histone H2AX

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19424844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and Alzheimer's Disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19424844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased oxidative damage to DNA in ALS patients

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19424844

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12 December 2020

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Diagnosis of Alzheimer's disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19424844

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12 December 2020

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Identifiers

DOI

10.1007/S11357-008-9050-7

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stated in

Europe PubMed Central

PMC publication ID

2585649

retrieved

17 August 2017

PMC publication ID

2585649

1 reference

stated in

Europe PubMed Central

PMC publication ID

2585649

retrieved

17 August 2017

PubMed publication ID

19424844

1 reference

stated in

Europe PubMed Central

PMC publication ID

2585649

retrieved

17 August 2017

ResearchGate publication ID

24410741

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