Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques (Q36952767)

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scientific article published on 13 December 2010

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English	Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques	scientific article published on 13 December 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Simian immunodeficiency virus

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inferred from title

Aftab A. Ansari

1

object named as

Aftab A Ansari

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Europe PubMed Central

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17 August 2017

Francois Villinger

13

object named as

Francois Villinger

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Europe PubMed Central

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17 August 2017

3

object named as

Ann E Mayne

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17 August 2017

author name string

Keith A Reimann

2

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17 August 2017

Yoshiaki Takahashi

4

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17 August 2017

Susan T Stephenson

5

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17 August 2017

Rijian Wang

6

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17 August 2017

Xinyue Wang

7

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17 August 2017

Jichu Li

8

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17 August 2017

Andrew A Price

9

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17 August 2017

Dawn M Little

10

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17 August 2017

Mohammad Zaidi

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17 August 2017

Robert Lyles

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publication date

13 December 2010

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17 August 2017

Journal of Immunology

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17 August 2017

186

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17 August 2017

2

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Europe PubMed Central

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17 August 2017

1044-1059

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Europe PubMed Central

PMC publication ID

17 August 2017

Innate Immune Natural Killer Cells and Their Role in HIV and SIV Infection

1 reference

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PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors

1 reference

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A novel chemokine-receptor-5 (CCR5) blocker, SCH532706, has differential effects on CCR5+CD4+ and CCR5+CD8+ T cell numbers in chronic HIV infection

1 reference

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Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine.

1 reference

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Targeting early infection to prevent HIV-1 mucosal transmission.

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IFN-alpha-induced upregulation of CCR5 leads to expanded HIV tropism in vivo

1 reference

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Preliminary in vivo efficacy studies of a recombinant rhesus anti-alpha(4)beta(7) monoclonal antibody.

1 reference

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Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection.

1 reference

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Is the gut the major source of virus in early simian immunodeficiency virus infection?

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HIV infection and the gastrointestinal immune system

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Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo

1 reference

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T-cell recruitment to the intestinal mucosa

1 reference

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Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells

1 reference

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Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking

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Mucosal immune dysfunction in AIDS pathogenesis.

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CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow

1 reference

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HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

1 reference

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The highway code of T cell trafficking.

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Homing imprinting and immunomodulation in the gut: role of dendritic cells and retinoids

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Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.

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HIV disease progression: immune activation, microbes, and a leaky gut.

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Differential homing mechanisms regulate regionalized effector CD8alphabeta+ T cell accumulation within the small intestine

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Generation of gut-homing T cells and their localization to the small intestinal mucosa

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

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HIV disease: fallout from a mucosal catastrophe?

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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

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Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

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Molecular mapping of functional antibody binding sites of alpha 4 integrin

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Sooty mangabeys and rhesus macaques exhibit significant divergent natural killer cell responses during both acute and chronic phases of SIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/21149598

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Expression and function of alpha4/beta7 integrin on human natural killer cells

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https://pubmed.ncbi.nlm.nih.gov/21149598

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Decreased CCR5 Expression on CD4+T Cells of SIV-Infected Sooty Mangabeys

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An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis

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Identifiers

10.4049/JIMMUNOL.1003052

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

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