Age dependency of cerebral P-gp function measured with (R)-[11C]verapamil and PET. (Q36947632)

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4 February 2020

title

Age dependency of cerebral P-gp function measured with (R)-[11C]verapamil and PET (English)

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4 February 2020

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Markus Alexander Zeitlinger

4 February 2020

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4 February 2020

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4 February 2020

Rudolf Karch

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4 February 2020

Friederike Neumann

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4 February 2020

Aiman Abrahim

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4 February 2020

Claudia C Wagner

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4 February 2020

Kurt Kletter

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4 February 2020

Markus Müller

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4 February 2020

publication date

5 August 2009

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European Journal of Clinical Pharmacology

4 February 2020

published in

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4 February 2020

volume

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4 February 2020

issue

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4 February 2020

page(s)

941-946

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P-glycoprotein function at the blood-brain barrier imaged using 11C-N-desmethyl-loperamide in monkeys

4 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Reduced 5-HT(2A) receptor signaling following selective bilateral amygdala damage.

29 September 2017

1 reference

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Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380.

29 September 2017

1 reference

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Tariquidar-induced P-glycoprotein inhibition at the rat blood-brain barrier studied with (R)-11C-verapamil and PET.

29 September 2017

1 reference

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Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA.

29 September 2017

1 reference

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Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases

29 September 2017

1 reference

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Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe

29 September 2017

1 reference

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Pharmacokinetics of (+)-, (-)- and (+/-)-verapamil after intravenous administration

27 June 2018

1 reference

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Locally increased P-glycoprotein function in major depression: a PET study with [11C]verapamil as a probe for P-glycoprotein function in the blood-brain barrier

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Blood-brain barrier P-glycoprotein function decreases in specific brain regions with aging: a possible role in progressive neurodegeneration

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Pharmacoresistance in epilepsy: a pilot PET study with the P-glycoprotein substrate R-[(11)C]verapamil

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Effect of age on functional P-glycoprotein in the blood-brain barrier measured by use of (R)-[(11)C]verapamil and positron emission tomography

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Evaluation of tracer kinetic models for quantification of P-glycoprotein function using (R)-[11C]verapamil and PET.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Pharmacokinetic consequences of active drug efflux at the blood-brain barrier

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Influence of functional haplotypes in the drug transporter gene ABCB1 on central nervous system drug distribution in humans

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Effect of mdr1a P-glycoprotein gene disruption, gender, and substrate concentration on brain uptake of selected compounds

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689922

Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19655132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00228-009-0709-5

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4 February 2020

1 reference

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4 February 2020

PubMed publication ID

19655132

1 reference

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