Apoptotic signal transduction and T cell tolerance (Q36922991)

17 August 2017

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title

Apoptotic signal transduction and T cell tolerance (English)

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17 August 2017

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Martina Gatzka

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17 August 2017

Craig M Walsh

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17 August 2017

publication date

1 September 2007

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17 August 2017

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17 August 2017

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17 August 2017

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17 August 2017

page(s)

442-452

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Molecular mechanisms of activated T cell death in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

BCL-2 family: regulators of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

A role for FADD in T cell activation and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The signaling adaptors and pathways activated by TNF superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The "fuzzy logic" of the death-inducing signaling complex in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Autoproteolytic activation of pro-caspases by oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

An induced proximity model for caspase-8 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Synthetic activation of caspases: artificial death switches

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Caspases at the crossroads of immune-cell life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The interplay between the Bcl-2 family and death receptor-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Induction of apoptosis in mature T cells by tumour necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Apoptotic and necrotic cell death induced by death domain receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Molecular mechanisms of TNF-alpha-induced apoptosis in aging human T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Perforin-mediated target-cell death and immune homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

NF-kappaB protects from the lysosomal pathway of cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Serine protease inhibitor 2A is a protective factor for memory T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Differential survival of cytotoxic T cells and memory cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Selection and fine-tuning of the autoimmune T-cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Projection of an immunological self shadow within the thymus by the aire protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Aire regulates negative selection of organ-specific T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Positional cloning of the APECED gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Back to central tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Control of T cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Thymocyte negative selection is mediated by protein kinase C- and Ca2+-dependent transcriptional induction of bim [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Bclx regulates the survival of double-positive thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

BCL-XL-regulated apoptosis in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Negative selection in the thymus includes semimature T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Normal thymocyte negative selection in TRAIL-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Caspase enzyme activity is not essential for apoptosis during thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Requirement for RORgamma in thymocyte survival and lymphoid organ development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

T cell receptor antagonist peptides induce positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Positive and negative selection invoke distinct signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Mechanisms of signaling by the hematopoietic-specific adaptor proteins, SLP-76 and LAT and their B cell counterpart, BLNK/SLP-65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

21 January 2018

The B7-CD28 superfamily

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Regulation of CD4 T cell memory by OX40 (CD134).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Peripheral tolerance of CD8 T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Requirement for transforming growth factor beta1 in controlling T cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Activation-induced cell death in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Delayed kinetics of T lymphocyte anergy and deletion in lpr mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Cutting edge: distinct TCR- and CD28-derived signals regulate CD95L, Bcl-xL, and the survival of primary T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Monoclonal IgM rheumatoid factors derived from arthritic MRL/Mp-lpr/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Molecular regulation of T lymphocyte homeostasis in the healthy and diseased immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Regulation of lymphocyte proliferation and death by FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Overexpression of the apoptosis inhibitor FLIP in T cells correlates with disease activity in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Surface expression of TRAIL/Apo-2 ligand in activated mouse T and B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

TRAIL/Apo-2-ligand-induced apoptosis in human T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The danger model: a renewed sense of self

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Toll-like receptor ligands directly promote activated CD4+ T cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Regulatory CD4+ T cells and the control of autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Distinct effects of STAT5 activation on CD4+ and CD8+ T cell homeostasis: development of CD4+CD25+ regulatory T cells versus CD8+ memory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Tolerance, not immunity, crucially depends on IL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The main function of IL-2 is to promote the development of T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Loss of Tolerance and Autoimmunity Affecting Multiple Organs inSTAT5A/5B-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Clearance of apoptotic and necrotic cells and its immunological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Lysosomes and autophagy in cell death control

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Cell death and immune privilege

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

Autoimmunity versus tolerance: can dying cells tip the balance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930701464962

10.1080/08916930701464962

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference