Keap1 eye on the target: chemoprevention of liver cancer (Q36920757)

17 August 2017

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title

Keap1 eye on the target: chemoprevention of liver cancer (English)

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17 August 2017

Melinda Sue Yates

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17 August 2017

Thomas Wells Kensler

series ordinal

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17 August 2017

publication date

1 September 2007

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Acta Pharmacologica Sinica

17 August 2017

published in

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17 August 2017

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17 August 2017

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17 August 2017

page(s)

1331-1342

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Chemoprevention of hepatocellular carcinoma in aflatoxin endemic areas

17 August 2017

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21 January 2018

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

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Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

21 January 2018

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Role of phase 2 enzyme induction in chemoprotection by dithiolethiones

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Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.

21 January 2018

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An electrophile responsive element (EpRE) regulates beta-naphthoflavone induction of the human gamma-glutamylcysteine synthetase regulatory subunit gene. Constitutive expression is mediated by an adjacent AP-1 site

21 January 2018

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Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

21 January 2018

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Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

21 January 2018

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21 January 2018

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Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1

21 January 2018

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Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 January 2018

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21 January 2018

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

21 January 2018

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21 January 2018

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Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis

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Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice

21 January 2018

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Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

21 January 2018

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10.1111/J.1745-7254.2007.00688.X

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

17 August 2017

1032430056

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