Nutrient supplementation with n3 polyunsaturated fatty acids, lutein, and zeaxanthin decrease A2E accumulation and VEGF expression in the retinas of Ccl2/Cx3cr1-deficient mice on Crb1rd8 background (Q36926292)

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scientific article published on 15 May 2013

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English	Nutrient supplementation with n3 polyunsaturated fatty acids, lutein, and zeaxanthin decrease A2E accumulation and VEGF expression in the retinas of Ccl2/Cx3cr1-deficient mice on Crb1rd8 background	scientific article published on 15 May 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Nutrient supplementation with n3 polyunsaturated fatty acids, lutein, and zeaxanthin decrease A2E accumulation and VEGF expression in the retinas of Ccl2/Cx3cr1-deficient mice on Crb1rd8 background (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

0 references

6

object named as

Emily Y Chew

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

7

object named as

Chi-Chao Chan

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

author name string

Hema L Ramkumar

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jingsheng Tuo

2

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Europe PubMed Central

PMC publication ID

17 August 2017

De F Shen

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jun Zhang

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Xiaoguang Cao

5

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Europe PubMed Central

PMC publication ID

17 August 2017

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publication date

15 May 2013

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Europe PubMed Central

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17 August 2017

Journal of Nutrition

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Europe PubMed Central

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17 August 2017

143

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Europe PubMed Central

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17 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1129-1135

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Early degeneration of photoreceptor synapse in Ccl2/Cx3cr1-deficient mice on Crb1(rd8) background

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1)

1 reference

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29 September 2017

IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Anti-inflammatory recombinant TSG-6 stabilizes the progression of focal retinal degeneration in a murine model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Neuroprotective effects of lutein in the retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Nutritional Supplementation and Age-Related Macular Degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

AAV5-mediated sFLT01 gene therapy arrests retinal lesions in Ccl2(-/-)/Cx3cr1(-/-) mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Naloxone ameliorates retinal lesions in Ccl2/Cx3cr1 double-deficient mice via modulation of microglia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Bisretinoids of RPE lipofuscin: trigger for complement activation in age-related macular degeneration

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29 September 2017

Relative contribution of VEGF and TNF-alpha in the cynomolgus laser-induced CNV model: comparing the efficacy of bevacizumab, adalimumab, and ESBA105.

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29 September 2017

Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).

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Low nitric oxide synthases (NOSs) in eyes with age-related macular degeneration (AMD).

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29 September 2017

A high omega-3 fatty acid diet reduces retinal lesions in a murine model of macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Does eating particular diets alter the risk of age-related macular degeneration in users of the Age-Related Eye Disease Study supplements?

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29 September 2017

A2E, a component of lipofuscin, is pro-angiogenic in vivo

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Omega-3 long-chain polyunsaturated fatty acid intake inversely associated with 12-year progression to advanced age-related macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Molecular pathology of age-related macular degeneration

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29 September 2017

The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

The role of vascular endothelial growth factor and other endogenous interplayers in age-related macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Ccl2/Cx3cr1-deficient mice: an animal model for age-related macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

The Relationship of Dietary Carotenoid and Vitamin A, E, and C Intake With Age-Related Macular Degeneration in a Case-Control Study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Carotenoids and antioxidants in age-related maculopathy italian study: multifocal electroretinogram modifications after 1 year

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial).

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681547

29 September 2017

A simple method for the isolation and purification of total lipides from animal tissues

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29 September 2017

Long-chain n-3 fatty acids and inflammation: potential application in surgical and trauma patients

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29 September 2017

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8

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29 September 2017

Review: effects of nitric oxide on eye diseases and their treatment

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29 September 2017

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells

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Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis

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29 September 2017

Docosahexaenoic acid modulates the interactions of the interphotoreceptor retinoid-binding protein with 11-cis-retinal

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Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration.

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27 June 2018

Lipopolysaccharide/interferon-gamma and not transforming growth factor beta inhibits retinal microglial migration from retinal explant

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Anti-angiogenic effect of luteolin on retinal neovascularization via blockade of reactive oxygen species production.

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Oral supplementation of lutein/zeaxanthin and omega-3 long chain polyunsaturated fatty acids in persons aged 60 years or older, with or without AMD.

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Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids in humans

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Retinal age pigments generated by self-assembling lysosomotropic detergents

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AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet

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Retinal light damage in rats with altered levels of rod outer segment docosahexaenoate

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https://pubmed.ncbi.nlm.nih.gov/23677863

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Ligand selectivity of the peroxisome proliferator-activated receptor alpha

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Associations Between Intermediate Age-Related Macular Degeneration and Lutein and Zeaxanthin in the Carotenoids in Age-Related Eye Disease Study (CAREDS)

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based on heuristic

inferred from PubMed ID database lookup

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10.3945/JN.112.169649

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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