Mutation analysis of gastrointestinal stromal tumors: increasing significance for risk assessment and effective targeted therapy (Q36911283)

17 August 2017

1 reference

title

Mutation analysis of gastrointestinal stromal tumors: increasing significance for risk assessment and effective targeted therapy (English)

1 reference

17 August 2017

author

Hans-Ulrich Schildhaus

series ordinal

object named as

Hans-Ulrich Schildhaus

0 references

Sabine Merkelbach-Bruse

series ordinal

object named as

Sabine Merkelbach-Bruse

0 references

Eva Wardelmann

series ordinal

object named as

Eva Wardelmann

1 reference

17 August 2017

Reinhard Büttner

1 reference

17 August 2017

publication date

14 August 2007

1 reference

17 August 2017

1 reference

17 August 2017

volume

451

1 reference

17 August 2017

1 reference

17 August 2017

page(s)

743-749

1 reference

Gastrointestinal stromal tumors (GIST)--current concepts of surgical management

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00428-007-0473-9

Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-007-0473-9

Gastrointestinal stromal tumors may originate from a subset of CD34-positive interstitial cells of Cajal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-007-0473-9

Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-007-0473-9

The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-007-0473-9

STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications

21 January 2018

1 reference

12 December 2020

Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival.

1 reference

12 December 2020

Gastrointestinal stromal tumors of the jejunum and ileum: a clinicopathologic, immunohistochemical, and molecular genetic study of 906 cases before imatinib with long-term follow-up

1 reference

12 December 2020

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

1 reference

12 December 2020

Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor.

1 reference

12 December 2020

Clinical management of gastrointestinal stromal tumors: before and after STI-571.

1 reference

12 December 2020

Gastrointestinal stromal tumors of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up

1 reference

12 December 2020

GISTs with PDGFRA exon 14 mutations represent subset of clinically favorable gastric tumors with epithelioid morphology

1 reference

12 December 2020

PDGFRA activating mutations in gastrointestinal stromal tumors.

1 reference

12 December 2020

Diagnosis of gastrointestinal stromal tumors: A consensus approach

1 reference

12 December 2020

Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial

1 reference

12 December 2020

An osteoclast-rich tumor of the gastrointestinal tract with features resembling clear cell sarcoma of soft parts: reports of 6 cases of a GIST simulator

1 reference

12 December 2020

Biphasic solitary fibrous tumour: a report of two cases with epithelioid features

1 reference

12 December 2020

Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors

1 reference

12 December 2020

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

1 reference

12 December 2020

Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal

1 reference

12 December 2020

PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib

1 reference

12 December 2020

PDGFRalpha- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features

1 reference

12 December 2020

Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors

1 reference

12 December 2020

c-kit gene mutation at exon 17 or 13 is very rare in sporadic gastrointestinal stromal tumors

1 reference

12 December 2020

Primary clear cell sarcoma of the ileum: an uncommon and misleading site

1 reference

12 December 2020

Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors

1 reference

12 December 2020

KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

1 reference

12 December 2020

Gastrointestinal stromal tumors with internal tandem duplications in 3' end of KIT juxtamembrane domain occur predominantly in stomach and generally seem to have a favorable course

1 reference

12 December 2020

Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate

1 reference

12 December 2020

CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34.

1 reference

12 December 2020

Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations

1 reference

12 December 2020

Gastrointestinal stromal tumors: pathology and prognosis at different sites

1 reference

12 December 2020

Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group

1 reference

12 December 2020

Inhibition of spontaneous receptor phosphorylation by residues in a putative alpha-helix in the KIT intracellular juxtamembrane region.

1 reference

12 December 2020

Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: a study by the Spanish Group for Sarcoma Research (GEIS).

1 reference

12 December 2020

PKCtheta expression in gastrointestinal stromal tumor

1 reference

12 December 2020

Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT)

1 reference

12 December 2020

CD34+ cells in human intestine are fibroblasts adjacent to, but distinct from, interstitial cells of Cajal

1 reference

12 December 2020

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

1 reference

12 December 2020

KIT-negative gastrointestinal stromal tumors: proof of concept and therapeutic implications

1 reference

12 December 2020

Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours

1 reference

12 December 2020

KIT activation is a ubiquitous feature of gastrointestinal stromal tumors

1 reference

12 December 2020

Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

1 reference

12 December 2020

Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

1 reference

12 December 2020

Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review

1 reference

12 December 2020

A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential

1 reference

12 December 2020

Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors

1 reference

12 December 2020

Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: clinicopathologic and immunohistochemical study of 26 cases

1 reference

12 December 2020

Gastrointestinal stromal tumors: recent advances in understanding of their biology

1 reference

12 December 2020

Clear cell sarcoma-like tumor with osteoclast-like giant cells in the small bowel: further evidence for a new tumor entity

1 reference

12 December 2020

Targeting c-kit mutations in solid tumors: scientific rationale and novel therapeutic options

1 reference

12 December 2020

Protein kinase C theta is highly expressed in gastrointestinal stromal tumors but not in other mesenchymal neoplasias.

1 reference

12 December 2020

10.1007/S00428-007-0473-9

Identifiers

DOI

1 reference

17 August 2017

1 reference