Endoplasmicreticulum-induced signal transduction and gene expression (Q36914444)

17 August 2017

title

Endoplasmicreticulum-induced signal transduction and gene expression (English)

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17 August 2017

H L Pahl

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17 August 2017

P A Baeuerle

series ordinal

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17 August 2017

publication date

1 February 1997

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17 August 2017

published in

Trends in Cell Biology

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17 August 2017

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17 August 2017

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17 August 2017

page(s)

50-55

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Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

17 August 2017

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The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

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A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

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tRNA ligase is required for regulated mRNA splicing in the unfolded protein response

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Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

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A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

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Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus

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Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors

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Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element

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Transactivation of the grp78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTF/NF-I

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Requirement of tyrosine- and serine/threonine kinases in the transcriptional activation of the mammalian grp78/BiP promoter by thapsigargin.

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Function and activation of NF-kappa B in the immune system

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

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7 January 2021

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

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7 January 2021

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

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7 January 2021

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

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7 January 2021

A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.

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Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention

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Regulation of the glucose-regulated protein genes by beta-mercaptoethanol requires de novo protein synthesis and correlates with inhibition of protein glycosylation

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Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

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7 January 2021

Calcium ionophore A23187 as a regulator of gene expression in mammalian cells

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7 January 2021

Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

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7 January 2021

Brefeldin A, thapsigargin, and AIF4- stimulate the accumulation of GRP78 mRNA in a cycloheximide dependent manner, whilst induction by hypoxia is independent of protein synthesis

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7 January 2021

Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B.

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Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance

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An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens

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The endoplasmic reticulum retention signal of the E3/19K protein of adenovirus type 2 consists of three separate amino acid segments at the carboxy terminus

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7 January 2021

Activation of NF-kappa B by ER stress requires both Ca2+ and reactive oxygen intermediates as messengers

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7 January 2021

A receptor-mediated pathway for cholesterol homeostasis

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7 January 2021

Regulation of the mevalonate pathway

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7 January 2021

Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene

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7 January 2021

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

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ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation

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Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain

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SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

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7 January 2021

Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

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7 January 2021

Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains

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7 January 2021

10.1016/S0962-8924(96)10050-7

Identifiers

DOI

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17 August 2017

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