Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion (Q36860874)

From Wikidata

Jump to navigation Jump to search

scientific article published on 12 November 2007

Language	Label	Description	Also known as
English	Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion	scientific article published on 12 November 2007

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

mitochondrial DNA

0 references

1 reference

based on heuristic

inferred from title

Drosophila melanogaster

object named as

Drosophila melanogaster

1 reference

based on heuristic

inferred from title

4

object named as

Carol L Farr

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Francisco Martínez-Azorín

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Manuel Calleja

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Rosana Hernández-Sierra

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Laurie S Kaguni

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Rafael Garesse

6

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

12 November 2007

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Journal of Neurochemistry

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

105

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

165-176

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

The radical scavenger CR-6 protects SH-SY5Y neuroblastoma cells from oxidative stress-induced apoptosis: effect on survival pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Differential patterns of apoptosis in response to aging in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Deficiency of the ADP-forming succinyl-CoA synthase activity is associated with encephalomyopathy and mitochondrial DNA depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

DNA polymerase gamma, the mitochondrial replicase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Mitochondrial respiratory-chain diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Mitochondrial protein import: two membranes, three translocases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Mitochondrial DNA depletion and dGK gene mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Life span: getting the signal from the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Animal mitochondrial biogenesis and function: a regulatory cross-talk between two genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Drosophila mitochondrial transcription factor A (d-TFAM) is dispensable for the transcription of mitochondrial DNA in Kc167 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Differential regulation of the catalytic and accessory subunit genes of Drosophila mitochondrial DNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

The highly compact structure of the mitochondrial DNA polymerase genomic region of Drosophila melanogaster: functional and evolutionary implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Motorneurons, reactive oxygen, and life span in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Functional interactions of mitochondrial DNA polymerase and single-stranded DNA-binding protein. Template-primer DNA binding and initiation and elongation of DNA strand synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Mitochondrial disease in mouse results in increased oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

TheSwiss CheeseMutant Causes Glial Hyperwrapping and Brain Degeneration inDrosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

4-Quinolones cause a selective loss of mitochondrial DNA from mouse L1210 leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Highly efficient DNA synthesis in isolated mitochondria from rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Gene disruptions using P transposable elements: an integral component of the Drosophila genome project

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Transposition of cloned P elements into Drosophila germ line chromosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

The behavior of four neurological mutants of Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Drosophila melanogaster mitochondrial DNA: gene organization and evolutionary considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Biogenesis of mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

mtDNA depletion with variable tissue expression: a novel genetic abnormality in mitochondrial diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

The mitochondrial DNA of drosophila melanogaster exists in two distinct and stable superhelical forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

29 September 2017

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

27 June 2018

Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

27 June 2018

Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

27 June 2018

Complete sequences of the rRNA genes of Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

27 June 2018

Mutation analysis in 16 patients with mtDNA depletion.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Drosophila grim induces apoptosis in mammalian cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Rates of behavior and aging specified by mitochondrial function during development

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Mitochondrial transcription factor A regulates mtDNA copy number in mammals

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

The respiratory chain complex thresholds in mitochondria of a Drosophila subobscura mutant strain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Overexpression of the catalytic subunit of DNA polymerase gamma results in depletion of mitochondrial DNA in Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Mitochondrial DNA polymerase gamma deficiency and mtDNA depletion in a child with Alpers' syndrome.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Oxidative stress hypothesis of aging.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Baculovirus expression reconstitutes Drosophila mitochondrial DNA polymerase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05122.X

21 January 2018

Mitochondrial DNA depletion is a prevalent cause of multiple respiratory chain deficiency in childhood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

4 September 2018

A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

4 September 2018

Late-onset corticohippocampal neurodepletion attributable to catastrophic failure of oxidative phosphorylation in MILON mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

4 September 2018

Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853903

4 September 2018

A simple ultraviolet spectrophotometric method for the determination of protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17999718

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1471-4159.2007.05122.X

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36860874&oldid=2087748891"