A block in endoplasmic reticulum-to-Golgi trafficking inhibits phospholipid synthesis and induces neutral lipid accumulation (Q36869495)

16 August 2017

A block in endoplasmic reticulum-to-Golgi trafficking inhibits phospholipid synthesis and induces neutral lipid accumulation (English)

1 reference

16 August 2017

endoplasmic reticulum

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Sepp D Kohlwein

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Maria L Gaspar

1 reference

16 August 2017

Stephen A Jesch

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16 August 2017

Raghuvir Viswanatha

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16 August 2017

Amy L Antosh

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16 August 2017

William J Brown

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16 August 2017

Susan A Henry

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16 August 2017

language of work or name

English

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publication date

9 July 2008

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Journal of Biological Chemistry

16 August 2017

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inferred from page(s)

published in

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16 August 2017

283

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16 August 2017

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16 August 2017

25735-25751

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describes a project that uses

16 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2533092/fullTextXML

inferred from PubMed Central ID database lookup

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29 September 2017

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29 September 2017

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Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

29 September 2017

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The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response

29 September 2017

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Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

29 September 2017

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The emergence of yeast lipidomics

29 September 2017

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Synthesis, storage and degradation of neutral lipids in yeast

29 September 2017

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On the mechanism of sensing unfolded protein in the endoplasmic reticulum

29 September 2017

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Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast

29 September 2017

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XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

29 September 2017

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Role of the unfolded protein response pathway in secretory stress and regulation of INO1 expression in Saccharomyces cerevisiae

29 September 2017

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IRE1-independent gain control of the unfolded protein response

29 September 2017

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Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid.

29 September 2017

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Triglyceride accumulation protects against fatty acid-induced lipotoxicity

29 September 2017

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Selective protein exit from yeast endoplasmic reticulum in absence of functional COPII coat component Sec13p.

29 September 2017

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Role of the unfolded protein response pathway in regulation of INO1 and in the sec14 bypass mechanism in Saccharomyces cerevisiae.

29 September 2017

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Isolation and characterization of new Saccharomyces cerevisiae mutants perturbed in nuclear pore complex assembly

29 September 2017

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Induction of secretory pathway components in yeast is associated with increased stability of their mRNA.

29 September 2017

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IN02, a positive regulator of lipid biosynthesis, is essential for the formation of inducible membranes in yeast

29 September 2017

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The DGA1 gene determines a second triglyceride synthetic pathway in yeast.

29 September 2017

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Transmission electron microscopy of yeast

29 September 2017

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

29 September 2017

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Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes

29 September 2017

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Structure and assembly of the Nup84p complex

29 September 2017

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Shr3p mediates specific COPII coatomer-cargo interactions required for the packaging of amino acid permeases into ER-derived transport vesicles

29 September 2017

1 reference

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MGA2 or SPT23 is required for transcription of the delta9 fatty acid desaturase gene, OLE1, and nuclear membrane integrity in Saccharomyces cerevisiae

29 September 2017

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Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

29 September 2017

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COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes

29 September 2017

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The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane

29 September 2017

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Sec31 encodes an essential component of the COPII coat required for transport vesicle budding from the endoplasmic reticulum

29 September 2017

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The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae

29 September 2017

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A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

29 September 2017

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A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores

29 September 2017

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Cloning and sequence of the SCS2 gene, which can suppress the defect of INO1 expression in an inositol auxotrophic mutant of Saccharomyces cerevisiae

29 September 2017

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Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

29 September 2017

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Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.

29 September 2017

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A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

29 September 2017

1 reference

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SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

myo-Inositol-1-phosphate synthase. Characteristics of the enzyme and identification of its structural gene in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Temperature-sensitive Saccharomyces cerevisiae mutant defective in lipid biosynthesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Plasma membrane expansion terminates in Saccharomyces cerevisiae secretion-defective mutants while phospholipid synthesis continues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Expression of the Saccharomyces cerevisiae inositol-1-phosphate synthase (INO1) gene is regulated by factors that affect phospholipid synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Triaglycerol metabolism in Saccharomyces cerevisiae relation to phospholipid synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Osmotic imbalance in inositol-starved spheroplasts of Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Growth and metabolism of inositol-starved Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Inositol induces a profound alteration in the pattern and rate of synthesis and turnover of membrane lipids in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Genome-wide analysis reveals inositol, not choline, as the major effector of Ino2p-Ino4p and unfolded protein response target gene expression in yeast

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Determination of yeast glycogen content by individual cell spectroscopy using image analysis.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Characterization of yeast sar1 temperature-sensitive mutants, which are defective in protein transport from the endoplasmic reticulum

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.

27 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802685200

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802685200

Effects of unsaturated fatty acid supplementation on phospholipid and triacylglycerol biosynthesis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802685200

Glycogen--a covalently linked component of the cell wall in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802685200

Storage lipid synthesis is non-essential in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802685200

Proliferation of the endoplasmic reticulum occurs normally in cells that lack a functional unfolded protein response

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533092

Yeast mutant defective in phosphatidylserine synthesis

4 September 2018

1 reference

12 December 2020

Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms

1 reference

12 December 2020

Regulatory role of phosphatidate phosphatase in triacylglycerol synthesis of Saccharomyces cerevisiae

1 reference

12 December 2020

Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by inositol. Inositol is an inhibitor of phosphatidylserine synthase activity

1 reference

12 December 2020

Northern blotting of RNA denatured in glyoxal without buffer recirculation

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M802685200

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

18614533

1 reference