Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice (Q36791739)

16 August 2017

Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice (English)

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16 August 2017

P Saftig

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16 August 2017

E Hunziker

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16 August 2017

O Wehmeyer

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16 August 2017

S Jones

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16 August 2017

A Boyde

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16 August 2017

W Rommerskirch

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16 August 2017

J D Moritz

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16 August 2017

P Schu

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16 August 2017

K von Figura

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16 August 2017

language of work or name

English

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publication date

1 November 1998

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Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

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16 August 2017

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16 August 2017

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16 August 2017

13453-13458

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

16 August 2017

1 reference

Design of potent and selective human cathepsin K inhibitors that span the active site

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Scanning electron microscopy of bone: instrument, specimen, and issues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Recent developments in the understanding of the pathophysiology of osteopetrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): six unique arylsulfatase B gene alleles causing variable disease phenotypes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Maps from two interspecific backcross DNA panels available as a community genetic mapping resource

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Human cathepsin O. Molecular cloning from a breast carcinoma, production of the active enzyme in Escherichia coli, and expression analysis in human tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Toward a molecular understanding of skeletal development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Inhibition of bone resorption by selective inactivators of cysteine proteinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary molecular cloning, sequencing and tissue distribution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Fluorescence microscopic demonstration of cathepsin K activity as the major lysosomal cysteine proteinase in osteoclasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Histochemistry and biochemistry of tartrate-resistant acid phosphatase (TRAP) and tartrate-resistant acid adenosine triphosphatase (TrATPase) in bone, bone marrow and spleen: implications for osteoclast ontogeny

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Preservation of cartilage matrix proteoglycans using cationic dyes chemically related to ruthenium hexaammine trichloride

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Bone and haematopoietic defects in mice lacking c-fos

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24840

Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorption

4 December 2018

1 reference

12 December 2020

In vivo and in vitro evidence for the involvement of cysteine proteinases in bone resorption

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12 December 2020

Phagocytosis of bone collagen by osteoclasts in two cases of pycnodysostosis

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12 December 2020

Stereology for anisotropic cells: application to growth cartilage

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12 December 2020

Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth

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12 December 2020

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

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12 December 2020

Degradation of collagen in the bone-resorbing compartment underlying the osteoclast involves both cysteine-proteinases and matrix metalloproteinases

1 reference

12 December 2020

Pycnodysostosis. Orthopedic aspects with a description of 14 new cases

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.95.23.13453

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16 August 2017

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16 August 2017

PubMed publication ID

9811821

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