Kinetics of Nitrite Reduction and Peroxynitrite Formation by Ferrous Heme in Human Cystathionine β-Synthase (Q36778803)

16 August 2017

Kinetics of Nitrite Reduction and Peroxynitrite Formation by Ferrous Heme in Human Cystathionine β-Synthase (English)

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16 August 2017

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12 June 2020

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12 June 2020

Sebastián Carballal

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12 June 2020

Ernesto Cuevasanta

1 reference

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12 June 2020

Carmen Gherasim

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12 June 2020

David P Ballou

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12 June 2020

Ruma Banerjee

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12 June 2020

language of work or name

English

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publication date

11 February 2016

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Journal of Biological Chemistry

16 August 2017

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12 June 2020

volume

291

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12 June 2020

issue

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12 June 2020

page(s)

8004-8013

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S-Adenosyl-l-methionine Modulates CO and NO• Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase

12 June 2020

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29 September 2017

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Real-time measurements of amino acid and protein hydroperoxides using coumarin boronic acid.

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NO* binds human cystathionine β-synthase quickly and tightly

29 September 2017

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Nitrite reductase activity and inhibition of H₂S biogenesis by human cystathionine ß-synthase

29 September 2017

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Kinetic and mechanistic considerations to assess the biological fate of peroxynitrite

29 September 2017

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Peroxynitrite, a stealthy biological oxidant

29 September 2017

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Kinetics of reversible reductive carbonylation of heme in human cystathionine β-synthase.

29 September 2017

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Allosteric communication between the pyridoxal 5'-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase

29 September 2017

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Characterization of the mechanism and magnitude of cytoglobin-mediated nitrite reduction and nitric oxide generation under anaerobic conditions

29 September 2017

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Effect of the disease-causing R266K mutation on the heme and PLP environments of human cystathionine β-synthase

29 September 2017

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29 September 2017

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Human neuroglobin functions as a redox-regulated nitrite reductase

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Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine -synthase

29 September 2017

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Peroxynitrite is the major species formed from different flux ratios of co-generated nitric oxide and superoxide: direct reaction with boronate-based fluorescent probe

29 September 2017

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Inactivation of cystathionine beta-synthase with peroxynitrite.

29 September 2017

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Heme regulation of human cystathionine beta-synthase activity: insights from fluorescence and Raman spectroscopy

29 September 2017

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Fast ferrous heme-NO oxidation in nitric oxide synthases

29 September 2017

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Chemical biology of peroxynitrite: kinetics, diffusion, and radicals.

29 September 2017

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Modulation of the heme electronic structure and cystathionine beta-synthase activity by second coordination sphere ligands: The role of heme ligand switching in redox regulation.

29 September 2017

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The new chemical biology of nitrite reactions with hemoglobin: R-state catalysis, oxidative denitrosylation, and nitrite reductase/anhydrase

29 September 2017

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Properties of an unusual heme cofactor in PLP-dependent cystathionine beta-synthase

29 September 2017

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A pathogenic linked mutation in the catalytic core of human cystathionine beta-synthase disrupts allosteric regulation and allows kinetic characterization of a full-length dimer

29 September 2017

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Dynamics of carbon monoxide binding to cystathionine beta-synthase

29 September 2017

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The heme of cystathionine beta-synthase likely undergoes a thermally induced redox-mediated ligand switch

29 September 2017

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Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control

29 September 2017

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Neuroglobin, nitric oxide, and oxygen: functional pathways and conformational changes

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Human cystathionine beta-synthase is a heme sensor protein. Evidence that the redox sensor is heme and not the vicinal cysteines in the CXXC motif seen in the crystal structure of the truncated enzyme

29 September 2017

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Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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27 June 2018

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Correction to Kinetics of Reversible Reductive Carbonylation of Heme in Human Cystathionine β-Synthase

27 June 2018

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5 September 2018

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Reactions of ferrous neuroglobin and cytoglobin with nitrite under anaerobic conditions

5 September 2018

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Ferrous human cystathionine beta-synthase loses activity during enzyme assay due to a ligand switch process

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Visualization of PLP-bound intermediates in hemeless variants of human cystathionine beta-synthase: evidence that lysine 119 is a general base

5 September 2018

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5 September 2018

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5 September 2018

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Characterization of NO binding to human cystathionine beta-synthase: possible implications of the effects of CO and NO binding to the human enzyme

5 September 2018

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Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes

5 September 2018

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Pyridoxal phosphate binding sites are similar in human heme-dependent and yeast heme-independent cystathionine beta-synthases. Evidence from 31P NMR and pulsed EPR spectroscopy that heme and PLP cofactors are not proximal in the human enzyme

5 September 2018

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Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease

5 September 2018

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Trypsin cleavage of human cystathionine beta-synthase into an evolutionarily conserved active core: structural and functional consequences

5 September 2018

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5 September 2018

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The possible role of hydrogen sulfide as an endogenous neuromodulator.

5 September 2018

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Homocysteine metabolism in pregnancies complicated by neural-tube defects

5 September 2018

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5 September 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.M116.718734

Characterization of the heme in human cystathionine beta-synthase by X-ray absorption and electron paramagnetic resonance spectroscopies

21 January 2018

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12 December 2020

Cooperativity in the dissociation of nitric oxide from hemoglobin

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12 December 2020

Mechanism of cysteine oxidation by peroxynitrite: An integrated experimental and theoretical study

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12 December 2020

Assignment of enzymatic functions to specific regions of the PLP-dependent heme protein cystathionine beta-synthase

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12 December 2020

Nitric Oxide Binding Properties of Neuroglobin

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12 December 2020

Kinetics and mechanism of the oxidation of human deoxyhemoglobin by nitrites

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12 December 2020

Evidence for heme-mediated redox regulation of human cystathionine beta-synthase activity

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12 December 2020

Characterization of the heme and pyridoxal phosphate cofactors of human cystathionine beta-synthase reveals nonequivalent active sites

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12 December 2020

Nitrite reductase activity of hemoglobin S (sickle) provides insight into contributions of heme redox potential versus ligand affinity

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12 December 2020

Oxidation of reduced diphosphopyridine nucleotide

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12 December 2020

Detrimental role of homocysteine in renal ischemia-reperfusion injury

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12 December 2020

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

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12 December 2020

Molecular analysis of patients affected by homocystinuria due to cystathionine beta-synthase deficiency: report of a new mutation in exon 8 and a deletion in intron 11

1 reference

9 November 2024

https://opencitations.net/index/api/v1/citations/10.1007/BF00711769

Identifiers

DOI

10.1074/JBC.M116.718734

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26867575%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26867575%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

26867575

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26867575%20AND%20SRC:MED&resulttype=core&format=json