Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo (Q36762401)

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27 February 2020

title

Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo (English)

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27 February 2020

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27 February 2020

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27 February 2020

Ludger Hauck

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27 February 2020

Daniela Grothe

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27 February 2020

Filip Konecny

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27 February 2020

Vivek Rao

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27 February 2020

Tak W Mak

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27 February 2020

language of work or name

English

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publication date

25 March 2013

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Proceedings of the National Academy of Sciences of the United States of America

27 February 2020

published in

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27 February 2020

volume

110

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27 February 2020

issue

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27 February 2020

page(s)

6085-6090

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Oxidized DJ-1 inhibits p53 by sequestering p53 from promoters in a DNA-binding affinity-dependent manner

27 February 2020

cites work

1 reference

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Parkinsonism due to mutations in PINK1, parkin, and DJ-1 and oxidative stress and mitochondrial pathways

29 September 2017

1 reference

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

29 September 2017

1 reference

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DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses

29 September 2017

1 reference

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RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

29 September 2017

1 reference

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DJ-1 decreases Bax expression through repressing p53 transcriptional activity

29 September 2017

1 reference

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DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

29 September 2017

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Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

29 September 2017

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Mitochondria-targeted redox probes as tools in the study of oxidative damage and ageing.

29 September 2017

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Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

29 September 2017

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Protein kinase cascades in the regulation of cardiac hypertrophy

29 September 2017

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Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

29 September 2017

1 reference

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Regulation of angiogenesis by hypoxia: role of the HIF system

29 September 2017

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

29 September 2017

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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

29 September 2017

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A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function

29 September 2017

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The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

29 September 2017

1 reference

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G alpha(i) and G alpha(o) are target proteins of reactive oxygen species

29 September 2017

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

29 September 2017

1 reference

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Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

29 September 2017

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Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats

29 September 2017

1 reference

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The management of chronic heart failure

29 September 2017

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Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

29 September 2017

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The cellular and molecular response of cardiac myocytes to mechanical stress.

29 September 2017

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Superoxide-driven aconitase FE-S center cycling

29 September 2017

1 reference

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8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions

28 June 2018

1 reference

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Enhanced ROS production by NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure

28 June 2018

1 reference

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A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

5 September 2018

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Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

5 September 2018

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Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure

5 September 2018

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Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction

5 September 2018

1 reference

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Requirement of activation of the extracellular signal-regulated kinase cascade in myocardial cell hypertrophy.

5 September 2018

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p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1303444110

21 January 2018

1 reference

12 December 2020

DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism

1 reference

12 December 2020

Reduced myocardial injury due to exogenous oxidants in pressure induced heart hypertrophy

1 reference

12 December 2020

Inactivation-reactivation of aconitase in Escherichia coli. A sensitive measure of superoxide radical

1 reference

12 December 2020

Evidence of oxidative stress in chronic heart failure in humans

1 reference

12 December 2020

Apoptosis in myocytes in end-stage heart failure

1 reference

12 December 2020

Apoptosis in the failing human heart

1 reference

12 December 2020

Increased oxidative stress in dilated cardiomyopathic heart failure

1 reference

12 December 2020

Altered high-energy phosphate metabolism predicts contractile dysfunction and subsequent ventricular remodeling in pressure-overload hypertrophy mice

1 reference

12 December 2020

Congestive heart failure: fifty years of progress

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1303444110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23530187%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

0 references

1 reference

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27 February 2020

PubMed publication ID

23530187

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23530187%20AND%20SRC:MED&resulttype=core&format=json