The aging brain: is function dependent on growth hormone/insulin-like growth factor-1 signaling? (Q36766867)

16 August 2017

The aging brain: is function dependent on growth hormone/insulin-like growth factor-1 signaling? (English)

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16 August 2017

B A Forshee

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16 August 2017

3 June 2006

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16 August 2017

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16 August 2017

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16 August 2017

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16 August 2017

173-180

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Long-lived Ames dwarf mice: Oxidative damage to mitochondrial DNA in heart and brain.

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Do deficiencies in growth hormone and insulin-like growth factor-1 (IGF-1) shorten or prolong longevity?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Neoplasms in rats treated with pituitary growth hormone; pulmonary and lymphatic tissues.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Genes that prolong life: relationships of growth hormone and growth to aging and life span

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

The effects of growth hormone and IGF-1 deficiency on cerebrovascular and brain ageing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

The essential role of IGF-I: lessons from the long-term study and treatment of children and adults with Laron syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Growth, growth hormone and cognitive functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Aspects of the neuroendocrine control of growth hormone secretion in ageing mammals.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Neuroendocrine and reproductive consequences of overexpression of growth hormone in transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Growth hormone, body composition, and aging

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Neuroendocrine biomarkers of aging in the rat.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Effects of human growth hormone in men over 60 years old

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Effects of long-term, low-dose growth hormone therapy on immune function and life expectancy of mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Growth hormone insufficiency during childhood has implications for later life

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Growth Hormone Deficiency, Brain Development, and Intelligence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Psychoendocrinological studies in dwarfed children and adolescents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Intelligence Structure and Personality in Various Types of Physical Handicap in Childhood and Adolescence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Cognitive changes during growth hormone replacement in adult men.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Dwarf mice and the ageing process.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Modulation of long-term memory and extinction responses induced by growth hormone (GH) and growth hormone releasing hormone (GHRH) in rats.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Assessment of the primary adrenal cortical and pancreatic hormone basal levels in relation to plasma glucose and age in the unstressed Ames dwarf mouse

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Personality adjustment of children and adolescents with hypopituitarism

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Effects of growth hormone substitution on mental performance in adults with growth hormone deficiency: a pilot study.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Psychological aspects in children and adolescents with hypopituitarism

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Effects of short term administration of recombinant human growth hormone to elderly people

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Psychological well-being before and after growth hormone treatment in adults with growth hormone deficiency

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

The little women of Loja--growth hormone-receptor deficiency in an inbred population of southern Ecuador

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Physical and psychological capabilities during substitution therapy with recombinant growth hormone in adults with growth hormone deficiency

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Insulin-like growth factor receptor expression and function in human breast cancer

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Long-term growth hormone treatment in growth hormone deficient adults

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Senescence-accelerated mouse (SAM): Age-related reduced anxiety-like behavior in the SAM-P/8 strain

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Cognitive and emotional functioning in hypopituitary short-statured children.

27 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11357-006-9005-9

Chronic [D-Ala2]-growth hormone-releasing hormone administration attenuates age-related deficits in spatial memory.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11357-006-9005-9

Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Differential effects of aging and insulin-like growth factor-1 on synapses in CA1 of rat hippocampus

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Could a deficiency in growth hormone signaling be beneficial to the aging brain?

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

HISTOLOGY OF THE ANTERIOR HYPOPHYSIS, THYROID AND GONADS OF TWO TYPES OF DWARF MICE.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Effects of physiological growth hormone (GH) therapy on cognition and quality of life in patients with adult-onset GH deficiency.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Normal intelligence with severe insulin-like growth factor I deficiency due to growth hormone receptor deficiency: a controlled study in a genetically homogeneous population

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Cognitive impairments and mood disturbances in growth hormone deficient men.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Quality of life in adults with growth hormone (GH) deficiency: response to treatment with recombinant human GH in a placebo-controlled 21-month trial

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Premature ageing in transgenic mice expressing different growth hormone genes

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Psychosocial adjustment in a large cohort of adults with growth hormone deficiency treated with growth hormone in childhood: summary of a questionnaire survey. Committee for the Study Group of Adult GH Deficiency.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Growth Hormone Treatment in Adults with Childhood Onset Growth Hormone Deficiency: Effects on Psychological Capabilities

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Dwarfism and hypoptiuitarism: statural retardation without mental retardation

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Psychological aspects of pituitary insufficiency in children and adolescents with special reference to growth hormone

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2464729

Increased plasma corticosterone levels in bovine growth hormone (bGH) transgenic mice: effects of ACTH, GH and IGF-I on in vitro adrenal corticosterone production

5 September 2018

1 reference

12 December 2020

Negative impact of growth-hormone deficiency on psychological functioning in dwarfed children and adolescents

1 reference

12 December 2020

Effects of growth hormone on hypothalamic catalase and Cu/Zn superoxide dismutase

1 reference

12 December 2020

The educational, vocational, and marital status of growth hormone-deficient adults treated with growth hormone during childhood

1 reference

12 December 2020

Age-associated loss of bone marrow hematopoietic cells is reversed by GH and accompanies thymic reconstitution

1 reference

12 December 2020

Aged-rodent models of long-term growth hormone therapy: lack of deleterious effect on longevity

1 reference

12 December 2020

Growth hormone for the elderly?

1 reference

12 December 2020

The effect of growth hormone administration in growth hormone deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as on body composition

1 reference

12 December 2020

Daily activity and body temperature rhythms do not change simultaneously with age in laboratory mice

1 reference

12 December 2020

Locomotor activity in female rhesus monkeys: assessment of age and calorie restriction effects

1 reference

12 December 2020

A note on adults with growth hormone deficiency

1 reference

12 December 2020

Down regulation of masked and unmasked insulin receptors in the liver of transgenic mice expressing bovine growth hormone gene

1 reference

12 December 2020

Decrease in cellular replicative potential in "giant" mice transfected with the bovine growth hormone gene correlates to shortened life span

1 reference

12 December 2020

Catalase expression in delayed and premature aging mouse models

1 reference

12 December 2020

Antioxidative mechanisms and plasma growth hormone levels: potential relationship in the aging process

1 reference

12 December 2020

10.1007/S11357-006-9005-9

Identifiers

DOI

1 reference

16 August 2017

1 reference

PMC publication ID

2464729

16 August 2017

PubMed publication ID

19943138

1 reference

PMC publication ID

2464729