The phosphatase-transcription activator EYA1 is targeted by anaphase-promoting complex/Cdh1 for degradation at M-to-G1 transition. (Q36757059)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23263983%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

The phosphatase-transcription activator EYA1 is targeted by anaphase-promoting complex/Cdh1 for degradation at M-to-G1 transition (English)

1 reference

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21 February 2020

1 reference

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21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23263983%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Zoi Karoulia

1 reference

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21 February 2020

Elaine Y M Wong

series ordinal

1 reference

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21 February 2020

Keiji Itoh

series ordinal

1 reference

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21 February 2020

Pin-Xian Xu

series ordinal

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21 February 2020

language of work or name

English

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publication date

21 December 2012

1 reference

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Molecular and Cellular Biology

21 February 2020

published in

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21 February 2020

volume

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21 February 2020

issue

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21 February 2020

page(s)

927-936

1 reference

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Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties

21 February 2020

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1 reference

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The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cells

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Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

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RING domain E3 ubiquitin ligases

29 September 2017

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Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

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Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear.

29 September 2017

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Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival.

29 September 2017

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29 September 2017

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Cell cycle regulation of the human Six1 homeoprotein is mediated by APC(Cdh1).

29 September 2017

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SUMO1 haploinsufficiency leads to cleft lip and palate

29 September 2017

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Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear

29 September 2017

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Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding

29 September 2017

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Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme

29 September 2017

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Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth.

29 September 2017

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Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes

29 September 2017

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Eyes absent represents a class of protein tyrosine phosphatases

29 September 2017

1 reference

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Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis

29 September 2017

1 reference

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The role of Six1 in mammalian auditory system development

29 September 2017

1 reference

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Six1 is required for the early organogenesis of mammalian kidney

29 September 2017

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Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway

29 September 2017

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Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid

29 September 2017

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The anaphase-promoting complex: proteolysis in mitosis and beyond

29 September 2017

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Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome

29 September 2017

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Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis

29 September 2017

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Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein

29 September 2017

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Mitotic regulation of the APC activator proteins CDC20 and CDH1

29 September 2017

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The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

29 September 2017

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Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya

29 September 2017

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Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia

29 September 2017

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Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

29 September 2017

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The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development

29 September 2017

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Mouse Eya genes are expressed during limb tendon development and encode a transcriptional activation function

29 September 2017

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29 September 2017

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A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family

29 September 2017

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Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode

29 September 2017

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The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.

29 September 2017

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29 September 2017

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How APC/C-Cdc20 changes its substrate specificity in mitosis

29 September 2017

1 reference

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Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623089

The transcription factor Eyes absent is a protein tyrosine phosphatase

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623089

Dachshund and Eyes Absent Proteins Form a Complex and Function Synergistically to Induce Ectopic Eye Development in Drosophila

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23263983

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.01516-12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23263983%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23263983%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

23263983

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23263983%20AND%20SRC:MED&resulttype=core&format=json