Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection (Q36699786)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18474629%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection (English)

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7 January 2020

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7 January 2020

Martin Holdener

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7 January 2020

Edith Hintermann

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7 January 2020

Monika Bayer

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7 January 2020

Antje Rhode

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7 January 2020

Evelyn Rodrigo

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7 January 2020

Gudrun Hintereder

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7 January 2020

Eric F Johnson

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7 January 2020

Frank J Gonzalez

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7 January 2020

Josef Pfeilschifter

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7 January 2020

Michael P Manns

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7 January 2020

Matthias von G Herrath

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7 January 2020

language of work or name

English

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publication date

12 May 2008

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Journal of Experimental Medicine

7 January 2020

published in

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7 January 2020

volume

205

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7 January 2020

issue

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7 January 2020

page(s)

1409-1422

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Pathogenic epitopes, heterologous immunity and vaccine design

7 January 2020

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30 September 2017

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30 September 2017

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The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity

30 September 2017

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30 September 2017

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Bacteria and human autoimmunity: the case of primary biliary cirrhosis

30 September 2017

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Induction, acceleration or prevention of autoimmunity by molecular mimicry

30 September 2017

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Microorganisms and autoimmunity: making the barren field fertile?

30 September 2017

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Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient

30 September 2017

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Hepatic T cells and liver tolerance

30 September 2017

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The CYP2D6 humanized mouse: effect of the human CYP2D6 transgene and HNF4alpha on the disposition of debrisoquine in the mouse.

30 September 2017

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Immunoreactivity to various human cytochrome P450 proteins of sera from patients with autoimmune hepatitis, chronic hepatitis B, and chronic hepatitis C.

30 September 2017

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Molecular mimicry: a critical look at exemplary instances in human diseases

30 September 2017

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International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis

30 September 2017

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Molecular mimicry of human cytochrome P450 by hepatitis C virus at the level of cytotoxic T cell recognition

30 September 2017

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Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

30 September 2017

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Molecular mimicry and immune-mediated diseases

30 September 2017

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Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice

30 September 2017

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30 September 2017

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Mechanisms of halothane toxicity: novel insights

30 September 2017

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Antibodies against human cytochrome P-450db1 in autoimmune hepatitis type II.

30 September 2017

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Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1.

30 September 2017

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LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase

30 September 2017

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30 September 2017

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Cytochrome P4502D6(193-212): a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease.

28 June 2018

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Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

28 June 2018

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28 June 2018

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Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

28 June 2018

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Identification of the main epitope on human cytochrome P450 IID6 recognized by anti-liver kidney microsome antibody

28 June 2018

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Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice

28 June 2018

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Liver/kidney microsome antibody type 1 and hepatitis C virus infection

28 June 2018

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Anti-GOR and hepatitis C virus in autoimmune liver diseases

28 June 2018

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Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2.

28 June 2018

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In vivo immune modulatory activity of hepatic stellate cells in mice

5 September 2018

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A new epitope of CYP2D6 recognized by liver kidney microsomal autoantibody from japanese patients with autoimmune hepatitis

5 September 2018

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Viral delivery of an epitope from Haemophilus influenzae induces central nervous system autoimmune disease by molecular mimicry

5 September 2018

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Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice

5 September 2018

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Cytochrome P450 2A6: a new hepatic autoantigen in patients with chronic hepatitis C virus infection

5 September 2018

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DNA vaccination breaks tolerance for a neo-self antigen in liver: a transgenic murine model of autoimmune hepatitis

5 September 2018

1 reference

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Diagnosis and treatment of autoimmune hepatitis

5 September 2018

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Differences in anti-LKM-1 autoantibody immunoreactivity to CYP2D6 antigenic sites between hepatitis C virus-negative and -positive patients

5 September 2018

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Visualizing the generation of memory CD4 T cells in the whole body

5 September 2018

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Break of T cell ignorance to a viral antigen in the liver induces hepatitis

5 September 2018

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5 September 2018

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Differential priming of CD8 and CD4 T-cells in animal models of autoimmune hepatitis and cholangitis

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20071859

Overlapping but distinct specificities of anti-liver-kidney microsome antibodies in autoimmune hepatitis type II and hepatitis C revealed by recombinant native CYP2D6 and novel peptide epitopes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20071859

Clonal analysis of liver-infiltrating T cells in patients with LKM-1 antibody-positive autoimmune chronic active hepatitis

21 January 2018

1 reference

12 December 2020

Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells

1 reference

12 December 2020

Selective retention of activated CD8+ T cells by the normal liver

1 reference

12 December 2020

Characterisation of a new subgroup of autoimmune chronic active hepatitis by autoantibodies against a soluble liver antigen

1 reference

12 December 2020

Identification and analysis of cytochrome P450IID6 antigenic sites recognized by anti‐liver‐kidney microsome type‐1 antibodies (LKM1)

1 reference

12 December 2020

Failure to induce organ-specific autoimmunity by breaking of tolerance: importance of the microenvironment

1 reference

12 December 2020

Molecular mimicry and autoimmune disease

1 reference

12 December 2020

Type 2 autoimmune hepatitis and hepatitis C virus infection

1 reference

12 December 2020

A major CYP2D6 autoepitope in autoimmune hepatitis type 2 and chronic hepatitis C is a three-dimensional structure homologous to other cytochrome P450 autoantigens

1 reference

12 December 2020

Autoreactive CD4+ LKM-specific and anticlonotypic T-cell responses in LKM-1 antibody-positive autoimmune hepatitis

1 reference

12 December 2020

Class I-restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20071859

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18474629%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18474629%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

18474629

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18474629%20AND%20SRC:MED&resulttype=core&format=json