Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma (Q36662044)

15 August 2017

Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma (English)

1 reference

15 August 2017

1 reference

Dirk Hose

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15 August 2017

Hartmut Goldschmidt

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15 August 2017

Elena Viziteu

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15 August 2017

Camille Grandmougin

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15 August 2017

Anja Seckinger

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15 August 2017

Bernard Klein

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15 August 2017

Jerome Moreaux

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15 August 2017

language of work or name

English

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publication date

11 February 2016

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British Journal of Cancer

15 August 2017

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15 August 2017

114

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15 August 2017

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15 August 2017

519-523

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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International

15 August 2017

start time

11 February 2016

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Epidithiodiketopiperazines (ETPs) exhibit in vitro antiangiogenic and in vivo antitumor activity by disrupting the HIF-1α/p300 complex in a preclinical model of prostate cancer

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Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma.

30 September 2017

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Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

30 September 2017

1 reference

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Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models.

30 September 2017

1 reference

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Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors

30 September 2017

1 reference

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Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma

30 September 2017

1 reference

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The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma.

30 September 2017

1 reference

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Targeting HIF1α eliminates cancer stem cells in hematological malignancies.

30 September 2017

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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

30 September 2017

1 reference

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Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma

30 September 2017

1 reference

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Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

30 September 2017

1 reference

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Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myeloma cells to melphalan

30 September 2017

1 reference

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Targeting angiogenesis via a c-Myc/hypoxia-inducible factor-1alpha-dependent pathway in multiple myeloma

30 September 2017

1 reference

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The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angio

30 September 2017

1 reference

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Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

30 September 2017

1 reference

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Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression.

30 September 2017

1 reference

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20 September 2018

Identifiers

DOI

10.1038/BJC.2016.20

1 reference

15 August 2017

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15 August 2017

PubMed publication ID

26867162

1 reference