Lectin-resistant CHO glycosylation mutants (Q36657268)

15 August 2017

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title

Lectin-resistant CHO glycosylation mutants (English)

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15 August 2017

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Santosh Kumar Patnaik

series ordinal

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15 August 2017

Pamela Stanley

series ordinal

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15 August 2017

language of work or name

English

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publication date

1 January 2006

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15 August 2017

published in

Methods in Enzymology

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15 August 2017

volume

416

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15 August 2017

page(s)

159-182

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Requirement of the Lec35 gene for all known classes of monosaccharide-P-dolichol-dependent glycosyltransferase reactions in mammals

15 August 2017

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7 January 2021

DPM1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by DPM3

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7 January 2021

Molecular cloning of two Arabidopsis UDP-galactose transporters by complementation of a deficient Chinese hamster ovary cell line.

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7 January 2021

Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen

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7 January 2021

Biosynthesis of mucin type O-glycans: lack of correlation between glycosyltransferase and sulfotransferase activities and CFTR expression

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7 January 2021

Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Five Lec1 CHO cell mutants have distinct Mgat1 gene mutations that encode truncated N-acetylglucosaminyltransferase I.

1 reference

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7 January 2021

Suppressors of alpha(1,3)fucosylation identified by expression cloning in the LEC11B gain-of-function CHO mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Independent Lec1A CHO glycosylation mutants arise from point mutations in N-acetylglucosaminyltransferase I that reduce affinity for both substrates. Molecular consequences based on the crystal structure of GlcNAc-TI.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells

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7 January 2021

ProteinC-Mannosylation Is Enzyme-catalysed and Uses Dolichyl-Phosphate-Mannose as a Precursor

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Mutants of the CMP-sialic acid transporter causing the Lec2 phenotype

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Animal cell mutants defective in glycosaminoglycan biosynthesis

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Selection of mammalian cell mutants in sphingolipid biosynthesis

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Lec3 Chinese Hamster Ovary Mutants Lack UDP-N-acetylglucosamine 2-Epimerase Activity Because of Mutations in the Epimerase Domain of the Gne Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

The Lec23 Chinese hamster ovary mutant is a sensitive host for detecting mutations in alpha-glucosidase I that give rise to congenital disorder of glycosylation IIb (CDG IIb).

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Neuronal protection in stroke by an sLex-glycosylated complement inhibitory protein

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7 January 2021

O Mannosylation of alpha-dystroglycan is essential for lymphocytic choriomeningitis virus receptor function

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Novel poly-GalNAcbeta1-4GlcNAc (LacdiNAc) and fucosylated poly-LacdiNAc N-glycans from mammalian cells expressing beta1,4-N-acetylgalactosaminyltransferase and alpha1,3-fucosyltransferase

1 reference

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7 January 2021

Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

A Mutation Causing a Reduced Level of Expression of Six β4-Galactosyltransferase Genes Is the Basis of the Lec19 CHO Glycosylation Mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Chinese hamster ovary (CHO) cells may express six beta 4-galactosyltransferases (beta 4GalTs). Consequences of the loss of functional beta 4GalT-1, beta 4GalT-6, or both in CHO glycosylation mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Genetic complementation reveals a novel human congenital disorder of glycosylation of type II, due to inactivation of the Golgi CMP-sialic acid transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Autocatalytic polysialylation of polysialyltransferase-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Isolation and characterization of temperature-sensitive mammalian cell cycle mutants

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Point mutations identified in Lec8 Chinese hamster ovary glycosylation mutants that inactivate both the UDP-galactose and CMP-sialic acid transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Molecular cloning and expression of GDP-D-mannose-4,6-dehydratase, a key enzyme for fucose metabolism defective in Lec13 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Multi-component protein complexes and Golgi membrane trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Mouse large can modify complex N- and mucin O-glycans on alpha-dystroglycan to induce laminin binding

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

LEC12 and LEC29 gain-of-function Chinese hamster ovary mutants reveal mechanisms for regulating VIM-2 antigen synthesis and E-selectin binding

1 reference

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7 January 2021

Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

alpha(1,3)fucosyltransferases expressed by the gain-of-function Chinese hamster ovary glycosylation mutants LEC12, LEC29, and LEC30.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Lec32 is a new mutation in Chinese hamster ovary cells that essentially abrogates CMP-N-acetylneuraminic acid synthetase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

A single point mutation resulting in an adversely reduced expression of DPM2 in the Lec15.1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Nonglucosylated oligosaccharides are transferred to protein in MI8-5 Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Gain-of-function Chinese hamster ovary mutants LEC18 and LEC14 each express a novel N-acetylglucosaminyltransferase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

On the nature of hereditable variation in cultured somatic cells

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Selection of lectin-resistant mutants of animal cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Glycosylation mutants of animal cells

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Chinese hamster ovary cell mutants with multiple glycosylation defects for production of glycoproteins with minimal carbohydrate heterogeneity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

A subclass of cell surface carbohydrates revealed by a CHO mutant with two glycosylation mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Molecular analysis of three gain-of-function CHO mutants that add the bisecting GlcNAc to N-glycans

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Molecular cloning of human GDP-mannose 4,6-dehydratase and reconstitution of GDP-fucose biosynthesis in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

The Caenorhabditis elegans gene, gly-2, can rescue the N-acetylglucosaminyltransferase V mutation of Lec4 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

A point mutation causes mistargeting of Golgi GlcNAc-TV in the Lec4A Chinese hamster ovary glycosylation mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Karyotypic heterogeneity in CHO cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

The gain-of-function Chinese hamster ovary mutant LEC11B expresses one of two Chinese hamster FUT6 genes due to the loss of a negative regulatory factor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

Characterization of cell surface carbohydrate receptors for Entamoeba histolytica adherence lectin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2916011-5

7 January 2021

10.1016/S0076-6879(06)16011-5

Identifiers

DOI

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15 August 2017

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