Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases (Q36619859)

15 August 2017

Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases (English)

1 reference

15 August 2017

Charlotte Kuperwasser

object named as

Charlotte Kuperwasser

1 reference

15 August 2017

Cong Zhu

1 reference

15 August 2017

Ankit Gupta

1 reference

15 August 2017

Victoria L Hall

1 reference

15 August 2017

Amy L Rayla

1 reference

15 August 2017

Ryan G Christensen

1 reference

15 August 2017

Benjamin Dake

1 reference

15 August 2017

Abirami Lakshmanan

1 reference

15 August 2017

Gary D Stormo

1 reference

15 August 2017

Scot A Wolfe

1 reference

15 August 2017

language of work or name

English

0 references

publication date

8 January 2013

1 reference

15 August 2017

Nucleic Acids Research

1 reference

15 August 2017

1 reference

15 August 2017

1 reference

15 August 2017

2455-2465

1 reference

Creative Commons Attribution-NonCommercial 3.0 Unported

15 August 2017

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3575815/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Zinc-finger nuclease-mediated targeted insertion of reporter genes for quantitative imaging of gene expression in sea urchin embryos.

30 September 2017

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An optimized two-finger archive for ZFN-mediated gene targeting

30 September 2017

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FLASH assembly of TALENs for high-throughput genome editing

30 September 2017

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Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

30 September 2017

1 reference

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The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

30 September 2017

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Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

30 September 2017

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Versatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors.

30 September 2017

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Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish

30 September 2017

1 reference

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In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases

30 September 2017

1 reference

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Genome Engineering With Zinc-Finger Nucleases

30 September 2017

1 reference

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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

30 September 2017

1 reference

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Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

30 September 2017

1 reference

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In vivo genome editing restores haemostasis in a mouse model of haemophilia

30 September 2017

1 reference

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p53 Gene repair with zinc finger nucleases optimised by yeast 1-hybrid and validated by Solexa sequencing

30 September 2017

1 reference

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A modified bacterial one-hybrid system yields improved quantitative models of transcription factor specificity

30 September 2017

1 reference

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Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases.

30 September 2017

1 reference

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Chemokine receptor 5 knockout strategies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

A TALE nuclease architecture for efficient genome editing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Genome editing with engineered zinc finger nucleases

30 September 2017

1 reference

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Targeting DNA double-strand breaks with TAL effector nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Delivering the goods: viral and non-viral gene therapy systems and the inherent limits on cargo DNA and internal sequences

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Breaking the code of DNA binding specificity of TAL-type III effectors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

A simple cipher governs DNA recognition by TAL effectors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

MEME SUITE: tools for motif discovery and searching

30 September 2017

1 reference

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An affinity-based scoring scheme for predicting DNA-binding activities of modularly assembled zinc-finger proteins.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

30 September 2017

1 reference

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Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Unexpected failure rates for modular assembly of engineered zinc fingers

30 September 2017

1 reference

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A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system

30 September 2017

1 reference

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Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

An improved zinc-finger nuclease architecture for highly specific genome editing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

MEME: discovering and analyzing DNA and protein sequence motifs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

A bacterial one-hybrid selection system for interrogating zinc finger-DNA interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Cell-free selection of zinc finger DNA-binding proteins using in vitro compartmentalization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Designing transcription factor architectures for drug discovery.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Chimeric nucleases stimulate gene targeting in human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Human zinc fingers as building blocks in the construction of artificial transcription factors.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Synergy between adjacent zinc fingers in sequence-specific DNA recognition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Zinc finger phage: affinity selection of fingers with new DNA-binding specificities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

In vitro selection of zinc fingers with altered DNA-binding specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

In vivo genome editing using a high-efficiency TALEN system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Adding fingers to an engineered zinc finger nuclease can reduce activity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Design, construction and in vitro testing of zinc finger nucleases.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Validated zinc finger protein designs for all 16 GNN DNA triplet targets

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575815

Preassembled zinc-finger arrays for rapid construction of ZFNs

21 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23303772

12 December 2020

inferred from PubMed ID database lookup

A Single Amino Acid Substitution in Zinc Finger 2 of Adr1p Changes its Binding Specificity at two Positions in UAS1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23303772

12 December 2020

inferred from PubMed ID database lookup

Physical basis of a protein-DNA recognition code

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23303772

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NAR/GKS1357

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23303772

1 reference