A single in vivo administration of bombesin antagonist RC-3095 reduces the levels and mRNA expression of epidermal growth factor receptors in MXT mouse mammary cancers (Q36601503)

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scientific article published on September 1997

Language	Label	Description	Also known as
English	A single in vivo administration of bombesin antagonist RC-3095 reduces the levels and mRNA expression of epidermal growth factor receptors in MXT mouse mammary cancers	scientific article published on September 1997

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

A single in vivo administration of bombesin antagonist RC-3095 reduces the levels and mRNA expression of epidermal growth factor receptors in MXT mouse mammary cancers (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

2

object named as

A V Schally

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

4

object named as

N Lamharzi

1 reference

Europe PubMed Central

15 August 2017

PMC publication ID

author name string

K Szepeshazi

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

G Halmos

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

K Groot

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

J E Horvath

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

0 references

publication date

1 September 1997

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

94

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

20

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

10913-10918

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Reduction in receptors for bombesin and epidermal growth factor in xenografts of human small-cell lung cancer after treatment with bombesin antagonist RC-3095.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Bimodal regulation of epidermal growth factor receptor by estrogen in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Anti-epidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic cancer cell line DU145.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Human cancer cells exhibit protein kinase C-dependent c-erbB-2 transmodulation that correlates with phosphatase sensitivity and kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Correlation between the effects of bombesin antagonists on cell proliferation and intracellular calcium concentration in Swiss 3T3 and HT-29 cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Growth factors in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Synergistic effects of bombesin and epidermal growth factor on cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

G Protein-Coupled Receptor Systems Involved in Cell Growth and Oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Epidermal growth factor regulates the expression of its own receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Biological effects and receptor binding affinities of new pseudononapeptide bombesin/GRP receptor antagonists with N-terminal d-Trp or d-Tpi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Emergence of MCF-7 cells overexpressing a transfected epidermal growth factor receptor (EGFR) under estrogen-depleted conditions: evidence for a role of EGFR in breast cancer growth and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Reconstitution of epidermal growth factor receptor transmodulation by platelet-derived growth factor in Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

30 September 2017

Calcium-inducible transmodulation of receptor tyrosine kinase activity

1 reference

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28 June 2018

Inhibitory effect of bombesin/gastrin-releasing peptide antagonist RC-3095 and luteinizing hormone-releasing hormone antagonist SB-75 on the growth of MCF-7 MIII human breast cancer xenografts in athymic nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Inhibitory effects of antagonists of bombesin/gastrin releasing peptide (GRP) and somatostatin analog (RC-160) on growth of HT-29 human colon cancers in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Inhibition of growth of MKN45 human gastric-carcinoma xenografts in nude mice by treatment with bombesin/gastrin-releasing-peptide antagonist (RC-3095) and somatostatin analogue RC-160.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Effect of somatostatin analog RC-160 and bombesin/gastrin releasing peptide antagonist RC-3095 on growth of PC-3 human prostate-cancer xenografts in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Regulation of epidermal growth factor receptor by progestins and glucocorticoids in human breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

N-isobutyryl-His-Trp-Ala-Val-D-Ala-His-Leu-NHMe (ICI 216140) a potent in vivo antaconist analogue of bombesin/gastrin releasing peptide (BN/GRP) derived from the C-terminal sequence lacking the final methionine residue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Small cell lung cancer bombesin receptors are antagonized by reduced peptide bond analogues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Two classes of antagonist interact with receptors for the mitogenic neuropeptides bombesin, bradykinin, and vasopressin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Mitogenic signalling through the bombesin receptor: role of a guanine nucleotide regulatory protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Synergistic Effects of Epidermal Growth Factor (EGF) and Insulin-Like Growth Factor I/Somatomedin C (IGF-I) on Keratinocyte Proliferation May Be Mediated by IGF-I Transmodulation of the EGF Receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Stimulation of calcium mobilization but not proliferation by bombesin and tachykinin neuropeptides in human small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Endocrine effects of new bombesin/gastrin-releasing peptide antagonists in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Dose-related involvement of CCK in bombesin-induced pancreatic growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Metabolic stability and tumor inhibition of bombesin/GRP receptor antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

28 June 2018

Bombesin stimulates intracellular Ca2+ mobilization but not proliferation on human colon cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

20 September 2018

Inhibitory effect of bombesin/gastrin-releasing peptide (GRP) antagonists RC-3950-II and RC-3095 on MCF-7 MIII human breast cancer xenografts in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

20 September 2018

Role of gastrin in bombesin-stimulated somatostatin release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23529

20 September 2018

Antagonists of bombesin/gastrin-releasing peptide inhibit growth of SW-1990 human pancreatic adenocarcinoma and production of cyclic AMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

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Distinct receptors mediate gastrin-releasing peptide and neuromedin beta-induced delay of gastric of liquids in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a radioimmunoassay for a pseudononapeptide bombesin/GRP antagonist with antitumor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative estimation of epidermal growth factor receptor and c-erbB-2 in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of bombesin/gastrin-releasing peptide antagonist RC-3095 and high dose of somatostatin analogue RC-160 on nitrosamine-induced pancreatic cancers in hamsters

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of epidermal growth factor receptor induced by alpha-interferon in human epidermoid cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High potency of a new bombesin antagonist (RC-3095) in inhibiting serum gastrin levels; comparison of different routes of administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonists of bombesin/gastrin-releasing peptides as adjuncts to agonists of luteinizing hormone-releasing hormone in the treatment of experimental prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of epidermal growth factor binding and receptor gene expression by hormones and growth factors in sheep pituitary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth inhibition of estrogen-dependent and estrogen-independent MXT mammary cancers in mice by the bombesin and gastrin-releasing peptide antagonist RC-3095

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of bombesin, gastrin-releasing peptide (GRP)(14-27) and bombesin/GRP receptor antagonist RC-3095 on growth of nitrosamine-induced pancreatic cancers in hamsters

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic acid normalizes the increased gene transcription rate of TGF-alpha and EGFR in head and neck cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of stimulatory effect of neuromedin C on pancreatic exocrine secretion in conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of epidermal growth factor receptors associated with lack of response to endocrine therapy in recurrent breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

based on heuristic

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The mechanism of action of gastrin releasing peptide (GRP) in stimulating avian gastric acid secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/9380734

12 December 2020

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Identifiers

10.1073/PNAS.94.20.10913

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1997PNAS...9410913S

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

0 references

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