Human regulatory T cells and their role in autoimmune disease (Q36563532)

14 August 2017

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title

Human regulatory T cells and their role in autoimmune disease (English)

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14 August 2017

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David A Hafler

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14 August 2017

Clare Baecher-Allan

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14 August 2017

publication date

1 August 2006

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14 August 2017

published in

Immunological Reviews

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14 August 2017

volume

212

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14 August 2017

page(s)

203-216

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Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

14 August 2017

cites work

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Applying a new generation of genetic maps to understand human inflammatory disease

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A haplotype map of the human genome

21 January 2018

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Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

21 January 2018

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An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

21 January 2018

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Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood

21 January 2018

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Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

21 January 2018

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CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

21 January 2018

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Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro

21 January 2018

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Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood.

21 January 2018

1 reference

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Helicobacter pylori-specific CD4+ CD25high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals

21 January 2018

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Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.

21 January 2018

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Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

21 January 2018

1 reference

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Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.

21 January 2018

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Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis

21 January 2018

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

21 January 2018

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Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

21 January 2018

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Inhibition of human CD4(+)CD25(+high) regulatory T cell function

21 January 2018

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On the ontogeny and physiology of regulatory T cells

21 January 2018

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A history of prostate cancer treatment

21 January 2018

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Suppressor T cells--they're back and critical for regulation of autoimmunity!

21 January 2018

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Suppressor T cells in human diseases

21 January 2018

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The peripheral generation of CD4+ CD25+ regulatory T cells

21 January 2018

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Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells

21 January 2018

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Peripheral human T cells sensitized in mixed leukocyte culture synthesize and express Ia-like antigens

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

The coexpression of CD45RA and CD45RO isoforms on T cells during the S/G2/M stages of cell cycle.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Early signaling defects in human T cells anergized by T cell presentation of autoantigen

21 January 2018

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Autoreactive T cells in healthy individuals

21 January 2018

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Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Decreased FOXP3 levels in multiple sclerosis patients

21 January 2018

1 reference

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Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II

21 January 2018

1 reference

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Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis

21 January 2018

1 reference

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CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

21 January 2018

1 reference

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Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

The role of CD4+ CD25+ immunoregulatory T cells in the induction of autoimmune gastritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

A human suppressor T cell clone which recognizes an autologous helper T cell clone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00417.X

10.1111/J.0105-2896.2006.00417.X

21 January 2018

Identifiers

DOI

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14 August 2017

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