Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion (Q36545609)

14 August 2017

Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion (English)

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14 August 2017

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Viola Heinzelmann-Schwarz

14 August 2017

Claire Henry

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Caroline Ford

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Estelle Llamosas

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object named as

Viola Heinzelmann-Schwarz

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14 August 2017

Estelle Llamosas

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14 August 2017

Alexandra Knipprath-Meszaros

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14 August 2017

Andreas Schoetzau

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14 August 2017

Ellen Obermann

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14 August 2017

Maya Fuenfschilling

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14 August 2017

Rosemarie Caduff

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14 August 2017

Daniel Fink

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14 August 2017

Neville Hacker

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14 August 2017

language of work or name

English

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publication date

20 October 2015

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14 August 2017

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14 August 2017

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14 August 2017

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14 August 2017

40310-40326

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describes a project that uses

14 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4741897/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4741897/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Over-expression of ROR2 and Wnt5a cooperatively correlates with unfavorable prognosis in patients with non-small cell lung cancer.

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Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1

30 September 2017

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High ROR2 expression in tumor cells and stroma is correlated with poor prognosis in pancreatic ductal adenocarcinoma.

30 September 2017

1 reference

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Up-regulation of ROR2 is associated with unfavorable prognosis and tumor progression in cervical cancer

30 September 2017

1 reference

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Expression of Ror2 mediates invasive phenotypes in renal cell carcinoma

30 September 2017

1 reference

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Ovarian cancer stem cells express ROR1, which can be targeted for anti-cancer-stem-cell therapy

30 September 2017

1 reference

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Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both β-catenin dependent and independent Wnt signalling.

30 September 2017

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ROR1 expression correlated with poor clinical outcome in human ovarian cancer

30 September 2017

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The tyrosine kinase receptor ROR1 is constitutively phosphorylated in chronic lymphocytic leukemia (CLL) cells.

30 September 2017

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The Wnt/β-catenin pathway in ovarian cancer: a review.

30 September 2017

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Receptor tyrosine kinase-like orphan receptor 2 (Ror2) expression creates a poised state of Wnt signaling in renal cancer.

30 September 2017

1 reference

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Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

30 September 2017

1 reference

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Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

30 September 2017

1 reference

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Careful selection of reference genes is required for reliable performance of RT-qPCR in human normal and cancer cell lines

30 September 2017

1 reference

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The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer

30 September 2017

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The Wnt gatekeeper SFRP4 modulates EMT, cell migration and downstream Wnt signalling in serous ovarian cancer cells

30 September 2017

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The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis

30 September 2017

1 reference

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NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth

30 September 2017

1 reference

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Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients

30 September 2017

1 reference

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Integrated genomic analyses of ovarian carcinoma

30 September 2017

1 reference

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Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer

30 September 2017

1 reference

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Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain

30 September 2017

1 reference

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Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization

30 September 2017

1 reference

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NF-kappaB as a critical link between inflammation and cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

Epigenetic silencing of SFRP5 is related to malignant phenotype and chemoresistance of ovarian cancer through Wnt signaling pathway

30 September 2017

1 reference

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TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

The non-canonical Wnt ligand, Wnt5a, is upregulated and associated with epithelial to mesenchymal transition in epithelial ovarian cancer.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

Cytoskeleton network and cellular migration modulated by nuclear-localized receptor tyrosine kinase ROR1.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein filamin A.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741897

21 September 2018

Identifiers

DOI

10.18632/ONCOTARGET.5643

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

26515598

1 reference