Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia (Q36512593)

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scientific article published on 19 November 2012

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English	Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia	scientific article published on 19 November 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia (English)

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Europe PubMed Central

PMC publication ID

14 August 2017

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Guido Marcucci

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John C Byrd

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Natarajan Muthusamy

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Natarajan Muthusamy

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Yicheng Mao

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Asha Ramanunni

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Carolyn Cheney

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David Jarjoura

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Bo Yu

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Li-Yuan Bai

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Sarah E M Herman

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Xinmei Wang

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Yan Jin

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Xiaokui Mo

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Kenneth K Chan

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Robert J Lee

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L James Lee

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publication date

19 November 2012

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14 August 2017

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121

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1

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136-147

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describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3538326/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Targeting microRNAs in cancer: rationale, strategies and challenges

1 reference

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Milatuzumab immunoliposomes induce cell death in CLL by promoting accumulation of CD74 on the surface of B cells

1 reference

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Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells

1 reference

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5-year survival in patients with relapsed or refractory chronic lymphocytic leukemia in a randomized, phase III trial of fludarabine plus cyclophosphamide with or without oblimersen

1 reference

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Toll-like receptors on B-CLL cells: expression and functional consequences of their stimulation

1 reference

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Molecular and cellular mechanisms of CLL: novel therapeutic approaches.

1 reference

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30 September 2017

Targeted delivery systems for oligonucleotide therapeutics

1 reference

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30 September 2017

Transferrin receptor-targeted lipid nanoparticles for delivery of an antisense oligodeoxyribonucleotide against Bcl-2.

1 reference

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30 September 2017

Antitumor activity of G3139 lipid nanoparticles (LNPs).

1 reference

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30 September 2017

BCL-2 family antagonists for cancer therapy

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Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells

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30 September 2017

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Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

1 reference

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Oblimersen for the treatment of patients with chronic lymphocytic leukemia

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Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia

1 reference

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Antisense and nonantisense effects of antisense Bcl-2 on multiple roles of Bcl-2 as a chemosensitizer in cancer therapy

1 reference

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Therapeutic potential of Toll-like receptor 9 activation

1 reference

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Nuclear factor-kappaB in cancer development and progression

1 reference

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A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC.

1 reference

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G3139 and other CpG-containing immunostimulatory phosphorothioate oligodeoxynucleotides are potent suppressors of the growth of human tumor xenografts in nude mice

1 reference

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Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia.

1 reference

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1 reference

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1 reference

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Role of Toll-like receptors in antisense and siRNA [corrected].

1 reference

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1 reference

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The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism

1 reference

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CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens

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https://pubmed.ncbi.nlm.nih.gov/23165478

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Identifiers

10.1182/BLOOD-2012-01-407742

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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