Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). (Q36503887)

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scientific article published on June 1998

Language	Label	Description	Also known as
English	Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	scientific article published on June 1998

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Serge Przedborski

2

object named as

S Przedborski

1 reference

Europe PubMed Central

14 August 2017

PMC publication ID

Vernice Jackson-Lewis

4

object named as

V Jackson-Lewis

1 reference

Europe PubMed Central

14 August 2017

PMC publication ID

author name string

J Ara

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

A B Naini

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

R R Trifiletti

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

J Horwitz

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

H Ischiropoulos

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

1 June 1998

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Europe PubMed Central

PMC publication ID

14 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PMC publication ID

14 August 2017

95

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

7659-7663

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

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Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superox

1 reference

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30 September 2017

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

1 reference

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30 September 2017

Evidence of neuronal oxidative damage in Alzheimer's disease.

1 reference

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30 September 2017

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

1 reference

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30 September 2017

Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis

1 reference

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30 September 2017

Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds

1 reference

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

1 reference

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30 September 2017

A single human gene encoding multiple tyrosine hydroxylases with different predicted functional characteristics

1 reference

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The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method

1 reference

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30 September 2017

Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis

1 reference

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The oxidant stress hypothesis in Parkinson's disease: evidence supporting it

1 reference

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30 September 2017

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

30 September 2017

Peroxynitrite-induced apoptosis in HL-60 cells

1 reference

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30 September 2017

Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation.

1 reference

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28 June 2018

Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

28 June 2018

Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

28 June 2018

Expression and characterization of catalytic and regulatory domains of rat tyrosine hydroxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

28 June 2018

Catalytic core of rat tyrosine hydroxylase: terminal deletion analysis of bacterially expressed enzyme.

1 reference

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28 June 2018

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

1 reference

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28 June 2018

Predicted amino acid sequence of bovine tyrosine hydroxylase and its similarity to tyrosine hydroxylases from other species

1 reference

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28 June 2018

Inactivation of tyrosine hydroxylase in rat striatum by 1-methyl-4-phenylpyridinium ion (MPP+).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

28 June 2018

Dose-dependent destruction of the coeruleus-cortical and nigral-striatal projections by MPTP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

28 June 2018

Change of tyrosine hydroxylase in the parkinsonian brain and in the brain of MPTP-treated mice as revealed by homospecific activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

28 June 2018

Measurement of tyrosine hydroxylase apoenzyme protein by enzyme-linked immunosorbent assay (ELISA): Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal tyrosine hydroxylase activity and content

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

28 June 2018

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22714

28 June 2018

Widespread peroxynitrite-mediated damage in Alzheimer's disease

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Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study

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Redox cycling of MPP+: evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase.

1 reference

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A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal

1 reference

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Nitric oxide and peroxynitrite-mediated pulmonary cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/9636206

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inferred from PubMed ID database lookup

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

1 reference

https://pubmed.ncbi.nlm.nih.gov/9636206

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Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine

1 reference

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Peroxynitrite‐Mediated Inhibition of DOPA Synthesis in PC12 Cells

1 reference

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inferred from PubMed ID database lookup

Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/9636206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9636206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9636206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbon dioxide enhancement of peroxynitrite-mediated protein tyrosine nitration

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.95.13.7659

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1998PNAS...95.7659A

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24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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