MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response. (Q36506250)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23104803%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23104803%20AND%20SRC:MED&resulttype=core&format=json

Mycobacterium tuberculosis

16 February 2020

main subject

0 references

1 reference

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16 February 2020

Xiuhua Pang

1 reference

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16 February 2020

Buka Samten

1 reference

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16 February 2020

Guangxiang Cao

1 reference

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16 February 2020

Xisheng Wang

1 reference

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16 February 2020

Amy R Tvinnereim

1 reference

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16 February 2020

Xiu-Lan Chen

1 reference

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16 February 2020

language of work or name

English

0 references

publication date

26 October 2012

1 reference

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16 February 2020

published in

Journal of Bacteriology

1 reference

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16 February 2020

volume

195

1 reference

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16 February 2020

issue

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16 February 2020

page(s)

66-75

1 reference

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Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

16 February 2020

cites work

1 reference

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Long-range transcriptional control of an operon necessary for virulence-critical ESX-1 secretion in Mycobacterium tuberculosis

30 September 2017

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The ins and outs of Mycobacterium tuberculosis protein export

30 September 2017

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Immune regulatory activities of early secreted antigenic target of 6-kD protein of Mycobacterium tuberculosis and implications for tuberculosis vaccine design

30 September 2017

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EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis.

30 September 2017

1 reference

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Computational analysis of the ESX-1 region of Mycobacterium tuberculosis: insights into the mechanism of type VII secretion system

30 September 2017

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The β-propeller gene Rv1057 of Mycobacterium tuberculosis has a complex promoter directly regulated by both the MprAB and TrcRS two-component systems.

30 September 2017

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Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis

30 September 2017

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Components of the Rv0081-Rv0088 locus, which encodes a predicted formate hydrogenlyase complex, are coregulated by Rv0081, MprA, and DosR in Mycobacterium tuberculosis

30 September 2017

1 reference

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EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins

30 September 2017

1 reference

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30 September 2017

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ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis

30 September 2017

1 reference

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EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity

30 September 2017

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30 September 2017

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A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine

30 September 2017

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Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence

30 September 2017

1 reference

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Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo

30 September 2017

1 reference

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Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536182

PepD participates in the mycobacterial stress response mediated through MprAB and SigE

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536182

Mycobacterium tuberculosis ESX-1 system-secreted protein ESAT-6 but not CFP10 inhibits human T-cell immune responses

30 September 2017

1 reference

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Phosphate depletion: a novel trigger for Mycobacterium tuberculosis persistence

30 September 2017

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ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria

30 September 2017

1 reference

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TB database: an integrated platform for tuberculosis research

30 September 2017

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Secreted transcription factor controls Mycobacterium tuberculosis virulence

30 September 2017

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ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection

30 September 2017

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Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

30 September 2017

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30 September 2017

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Regulation of the alpha-crystallin gene acr2 by the MprAB two-component system of Mycobacterium tuberculosis

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor

30 September 2017

1 reference

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Identification and characterization of a regulatory sequence recognized by Mycobacterium tuberculosis persistence regulator MprA

30 September 2017

1 reference

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A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion

30 September 2017

1 reference

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The extra cytoplasmic function sigma factor sigma(E) is essential for Mycobacterium tuberculosis virulence in mice

30 September 2017

1 reference

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The temporal expression profile of Mycobacterium tuberculosis infection in mice.

30 September 2017

1 reference

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Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

30 September 2017

1 reference

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The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

30 September 2017

1 reference

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Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system

30 September 2017

1 reference

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Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment

30 September 2017

1 reference

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Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation

30 September 2017

1 reference

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Microarray analysis of the Mycobacterium tuberculosis transcriptional response to the acidic conditions found in phagosomes

30 September 2017

1 reference

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Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications

30 September 2017

1 reference

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Mycobacterium tuberculosis signal transduction system required for persistent infections

30 September 2017

1 reference

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The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536182

Induction of direct antimicrobial activity through mammalian toll-like receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536182

Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536182

Transcriptional control of the iron-responsive fxbA gene by the mycobacterial regulator IdeR.

30 September 2017

1 reference

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Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

30 September 2017

1 reference

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aprABC: a Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536182

Global transcriptional response to vancomycin in Mycobacterium tuberculosis.

28 June 2018

1 reference

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Enhanced capacity of a widespread strain of Mycobacterium tuberculosis to grow in human macrophages

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536182

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536182

Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant of Mycobacterium tuberculosis

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23104803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23104803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JB.01067-12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23104803%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23104803%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

23104803

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23104803%20AND%20SRC:MED&resulttype=core&format=json