Clinical and pathological roles of Ro/SSA autoantibody system. (Q36469094)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23304190%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

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title

Clinical and pathological roles of Ro/SSA autoantibody system (English)

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22 February 2020

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22 February 2020

Atsuhisa Ueda

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22 February 2020

Keiko Ozato

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22 February 2020

Yoshiaki Ishigatsubo

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Clinical and Developmental Immunology

22 February 2020

published in

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2012

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30 September 2017

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The location of a disease-associated polymorphism and genomic structure of the human 52-kDa Ro/SSA locus (SSA1)

30 September 2017

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30 September 2017

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Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity

30 September 2017

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Interstitial pneumonitis in antinuclear antibody-negative systemic lupus erythematosus: a new clinical manifestation and possible association with anti-Ro (SS-A) antibodies

30 September 2017

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Molecular analysis of the 60-kDa human Ro ribonucleoprotein

30 September 2017

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Acquired congenital heart block. Pattern of maternal antibody response to biochemically defined antigens of the SSA/Ro-SSB/La system in neonatal lupus

30 September 2017

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Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen

30 September 2017

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Biochemical and immunological heterogeneity of the Ro ribonucleoprotein particles. Analysis with sera specific for the RohY5 particle

30 September 2017

1 reference

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Systemic lupus erythematosus: a review of clinico-laboratory features and immunogenetic markers in 150 patients with emphasis on demographic subsets

30 September 2017

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Specific amino acid residues in the second hypervariable region of HLA-DQA1 and DQB1 chain genes promote the Ro (SS-A)/La (SS-B) autoantibody responses.

30 September 2017

1 reference

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Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen

30 September 2017

1 reference

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Protein heterogeneity in the human Ro/SSA ribonucleoproteins. The 52- and 60-kD Ro/SSA autoantigens are encoded by separate genes

30 September 2017

1 reference

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Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation

30 September 2017

1 reference

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Antinuclear antibodies in Sjögren's syndrome

30 September 2017

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Autoantibodies to the Ro/SSA autoantigen are conformation dependent. II: Antibodies to the denatured form of 52 kD Ro/SSA are a cross reacting subset of antibodies to the native 60 kD Ro/SSA molecule

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Antibodies to cellular antigens in Sjögren's syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Resolution of the identity of certain antigen-antibody systems in systemic lupus erythematosus and sjögren's syndrome: An interlaboratory collaboration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

The clinical significance of autoantibodies to a soluble cytoplasmic antigen in systemic lupus erythematosus and other connective tissue diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

A soluble acidic protein of the cell nucleus which reacts with serum from patients with systemic lupus erythermatosus and Sjögren's syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Cutaneous diseases in adults associated with anti-Ro/SS-A autoantibody production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Two Ro (SS-A) autoantibody responses in systemic lupus erythematosus. Correlation of HLA-DR/DQ specificities with quantitative expression of Ro (SS-A) autoantibody

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

The 52 000 MW Ro/SS-A autoantigen in Sjögren's syndrome/systemic lupus erythematosus (Ro52) is an interferon-gamma inducible tripartite motif protein associated with membrane proximal structures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Immunoserological aspects of idiopathic inflammatory muscle disease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Prevalence and clinical relevance of 52-kDa and 60-kDa Ro/SS-A autoantibodies in Japanese patients with systemic sclerosis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Classification criteria for the idiopathic inflammatory myopathies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Gene interaction at HLA-DQ enhances autoantibody production in primary Sjögren's syndrome.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Maternal antibodies against fetal cardiac antigens in congenital complete heart block

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Virus infection induces redistribution and membrane localization of the nuclear antigen La (SS-B): a possible mechanism for autoimmunity.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Binding of antibodies to the extractable nuclear antigens SS-A/Ro and SS-B/La is induced on the surface of human keratinocytes by ultraviolet light (UVL): implications for the pathogenesis of photosensitive cutaneous lupus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Prolonged corrected QT interval in anti-Ro/SSA-positive adults with systemic lupus erythematosus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Clinical significance of anti-Ro52 (TRIM21) antibodies non-associated with anti-SSA 60kDa antibodies: results of a multicentric study

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Significance of antibodies to soluble liver antigen/liver pancreas: a large French study.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Characteristics of interstitial lung disease in SS-A positive/Jo-1 positive inflammatory myopathy patients.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Anti-Ro antibody and cutaneous vasculitis in systemic lupus erythematosus.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

A novel polymorphism of the SSA1 gene is associated with anti-SS-A/Ro52 autoantibody in Japanese patients with primary Sjögren's syndrome.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Prolongation of the corrected QT interval in adult patients with anti-Ro/SSA-positive connective tissue diseases

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Anti-Ro52 reactivity is an independent and additional serum marker in connective tissue disease

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Polymorphisms of the Ro52 gene associated with anti-Ro 52-kd autoantibodies in patients with primary Sjögren's syndrome

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Anti-52 kDa Ro(SSA) autoantibodies in different autoimmune diseases preferentially recognize epitopes on the central region of the antigen.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

A possible role for the 60-kD Ro autoantigen in a discard pathway for defective 5S rRNA precursors.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

Antibodies to SS-A/Ro-52kD and centromere in autoimmune liver disease: a clue to diagnosis and prognosis of primary biliary cirrhosis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523155

The association of anti-Ro52 autoantibodies with myositis and scleroderma autoantibodies

21 October 2018

1 reference

12 December 2020

Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies

1 reference

12 December 2020

Expression of SS-A/Ro and SS-B/La antigens in skin biopsy specimens of patients with photosensitive forms of lupus erythematosus

1 reference

12 December 2020

Sjögren's syndrome in progressive systemic sclerosis

1 reference

12 December 2020

Homozygous C2 deficiency, lupus erythematosus, and anti-Ro (SSA) antibodies

1 reference

12 December 2020

Prevalence of 52-kd and 60-kd Ro/SS-A autoantibodies in Japanese patients with polymyositis/dermatomyositis

1 reference

12 December 2020

Serological findings in patients with "ANA-negative" systemic lupus erythematosus

1 reference

12 December 2020

One hundred anti-Ro (SS-A) antibody positive patients: a 10-year follow-up

1 reference

12 December 2020

The presence of Sjögren's syndrome is a major determinant of the pattern of interstitial lung disease in scleroderma and other connective tissue diseases

1 reference

12 December 2020

Sjöugren's syndrome influence of multiple hla-d region alloantigens on clinical and serologic expression

1 reference

12 December 2020

Neonatal lupus risk to newborns of mothers with systemic lupus erythematosus

1 reference

12 December 2020

Systemic lupus erythematosus in the elderly: clinical and serological characteristics

1 reference

12 December 2020

Comparison of frequency of complex ventricular arrhythmias in patients with positive versus negative anti-Ro/SSA and connective tissue disease

1 reference

12 December 2020

In patients with antisynthetase syndrome the occurrence of anti-Ro/SSA antibodies causes a more severe interstitial lung disease

1 reference

12 December 2020

Immunogenetics of the neonatal lupus syndrome

1 reference

12 December 2020

STAT1-dependent and STAT1-independent gene expression in murine immune cells following stimulation with interferon-alpha

1 reference

12 December 2020

Serial analysis of Ro/SSA and La/SSB antibody levels and correlation with clinical disease activity in patients with systemic lupus erythematosus

1 reference

12 December 2020

Ro ribonucleoprotein assembly in vitro. Identification of RNA-protein and protein-protein interactions

1 reference

12 December 2020

Prognostic factors for the clinical severity of keratoconjunctivitis sicca in patients with Sjogren's syndrome

1 reference

12 December 2020

Anti-SS-A antibody and other antinuclear antibodies in systemic lupus erythematosus

1 reference

12 December 2020

Deforming arthropathy of the hands in systemic lupus erythematosus is associated with antibodies to SSA/Ro and to SSB/La

1 reference

12 December 2020

Anti-Ro/SS-A and anti-La/SS-B autoantibody levels in relation to systemic lupus erythematosus disease activity and congenital heart block. A longitudinal study comprising two consecutive pregnancies in a patient with systemic lupus erythematosus

1 reference

12 December 2020

Systemic lupus erythematosus in hereditary deficiency of the fourth component of complement

1 reference

12 December 2020

Identification and management of fetuses at risk for, or affected by, congenital heart block associated with autoantibodies to SSA (Ro), SSB (La), or an HsEg5-like autoantigen

1 reference

12 December 2020

Estradiol enhances binding to cultured human keratinocytes of antibodies specific for SS-A/Ro and SS-B/La. Another possible mechanism for estradiol influence of lupus erythematosus

1 reference

12 December 2020

Correlation of anti-Ro antibody with photosensitivity rash in systemic lupus erythematosus patients

1 reference

12 December 2020

Neonatal lupus syndromes

1 reference

12 December 2020

Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen

1 reference

12 December 2020

The relationship between anti-Ro (SS-A) antibody-positive Sjögren's syndrome and anti-Ro (SS-A) antibody-positive lupus erythematosus

1 reference

12 December 2020

Localization of Ro (SS-A) antigen in the cardiac conduction system

1 reference

12 December 2020

Purification of antigenically intact Ro ribonucleoproteins; biochemical and immunological evidence that the 52-kD protein is not a Ro protein

1 reference

12 December 2020

Ro/SS-A and La/SS-B antibody level variation in patients with Sjögren's syndrome and systemic lupus erythematosus

1 reference

12 December 2020

Risk of congenital complete heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis: a prospective study of 100 women

1 reference

12 December 2020

The importance of the level of maternal anti-Ro/SSA antibodies as a prognostic marker of the development of cardiac neonatal lupus erythematosus a prospective study of 186 antibody-exposed fetuses and infants

1 reference

12 December 2020

Anti-Ro/SSA antibodies in rheumatoid arthritis: clinical and immunologic associations

1 reference

12 December 2020

Autoantibodies to the Ro/SSA antigen are conformation dependent. I: Anti-60 kD antibodies are mainly directed to the native protein; anti-52 kD antibodies are mainly directed to the denatured protein

1 reference

12 December 2020

Anti-Ro/SSA antibodies are an independent factor associated with an insufficient response to tumor necrosis factor inhibitors in patients with rheumatoid arthritis

1 reference

12 December 2020

A serological marker for neonatal lupus erythematosus

1 reference

12 December 2020

Anti-Ro (SS-A) and anti-La (SS-B) in patients with Sjögren's syndrome

1 reference

12 December 2020

Incidence and spectrum of neonatal lupus erythematosus: a prospective study of infants born to mothers with anti-Ro autoantibodies

1 reference

12 December 2020

Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus

1 reference

12 December 2020

Identification of mothers at risk for congenital heart block and other neonatal lupus syndromes in their children. Comparison of enzyme-linked immunosorbent assay and immunoblot for measurement of anti-SS-A/Ro and anti-SS-B/La antibodies

1 reference

12 December 2020

Association of neutropenia in systemic lupus erythematosus (SLE) with anti-Ro and binding of an immunologically cross-reactive neutrophil membrane antigen

1 reference

12 December 2020

Rheumatoid arthritis: anti-Ro antibodies define a non-HLA-DR4 associated clinicoserological cluster

1 reference

12 December 2020

Serological profiles as prognostic clues for progressive systemic scleroderma: the Italian experience

1 reference

12 December 2020

Anti-Ro52 antibodies frequently co-occur with anti-Jo-1 antibodies in sera from patients with idiopathic inflammatory myopathy

1 reference

12 December 2020

Precipitating autoantibodies in Sjogren's disease

1 reference

12 December 2020

Association of maternal systemic lupus erythematosus with congenital complete heart block

1 reference

12 December 2020

Fluctuation of anti-Ro/SS-A antibody levels in patients with systemic lupus erythematosus and Sjögren's syndrome: a prospective study

1 reference

12 December 2020

Clinical implications of the presence of anti-Ro (SSA) antibodies in patients with rheumatoid arthritis

1 reference

12 December 2020

Sera from patients with autoimmune disease recognize conformational determinants on the 60-kd ro/ss-a protein

1 reference

12 December 2020

Characterization of a soluble cytoplasmic antigen reactive with sera from patients with systemic lupus erythmatosus

1 reference

12 December 2020

Anti-Ro(SS-A) antibody positive Sjögren's/lupus erythematosus overlap syndrome

1 reference

12 December 2020

Prognostic implications of antibodies to Ro/SSA and soluble liver antigen in type 1 autoimmune hepatitis

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/606195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23304190%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23304190%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

23304190

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23304190%20AND%20SRC:MED&resulttype=core&format=json