Model of the toxic complex of anthrax: responsive conformational changes in both the lethal factor and the protective antigen heptamer (Q36458615)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16943448%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Model of the toxic complex of anthrax: responsive conformational changes in both the lethal factor and the protective antigen heptamer (English)

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29 December 2019

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29 December 2019

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29 December 2019

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29 December 2019

Charles L Brooks

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29 December 2019

publication date

1 September 2006

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29 December 2019

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29 December 2019

volume

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29 December 2019

issue

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29 December 2019

page(s)

2190-2200

1 reference

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Crystallographic R factor refinement by molecular dynamics

29 December 2019

cites work

1 reference

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Structure of the E. coli protein-conducting channel bound to a translating ribosome

30 September 2017

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A model of anthrax toxin lethal factor bound to protective antigen.

30 September 2017

1 reference

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Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel

30 September 2017

1 reference

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Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Normal mode based flexible fitting of high-resolution structure into low-resolution experimental data from cryo-EM.

30 September 2017

1 reference

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Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation

30 September 2017

1 reference

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Crystal structure of a complex between anthrax toxin and its host cell receptor

30 September 2017

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MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology.

30 September 2017

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Domain Motions in GroEL upon Binding of an Oligopeptide

30 September 2017

1 reference

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Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins

30 September 2017

1 reference

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A graph-theory algorithm for rapid protein side-chain prediction

30 September 2017

1 reference

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Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy

30 September 2017

1 reference

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Locking and unlocking of ribosomal motions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Study of the structural dynamics of the E coli 70S ribosome using real-space refinement

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

A cryo-electron microscopic study of ribosome-bound termination factor RF2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Identification of amino acid residues of anthrax protective antigen involved in binding with lethal factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

PA63 channel of anthrax toxin: an extended beta-barrel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Stoichiometry of anthrax toxin complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Crystal structure of the anthrax lethal factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Identification of the cellular receptor for anthrax toxin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Using situs for flexible and rigid-body fitting of multiresolution single-molecule data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Bridging the information gap: computational tools for intermediate resolution structure interpretation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Ratiometric single-molecule studies of freely diffusing biomolecules.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Involvement of residues 147VYYEIGK153 in binding of lethal factor to protective antigen of Bacillus anthracis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Anisotropy of fluctuation dynamics of proteins with an elastic network model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

A ratchet-like inter-subunit reorganization of the ribosome during translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

A quantitative study of the interactions of Bacillus anthracis edema factor and lethal factor with activated protective antigen

30 September 2017

1 reference

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Situs: A package for docking crystal structures into low-resolution maps from electron microscopy

30 September 2017

1 reference

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Characterization of membrane translocation by anthrax protective antigen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Identification of residues lining the anthrax protective antigen channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Crystal structure of the anthrax toxin protective antigen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Anthrax toxin-mediated delivery of a cytotoxic T-cell epitope in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Anthrax protective antigen forms oligomers during intoxication of mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Dynamics of a small globular protein in terms of low-frequency vibrational modes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Simplified normal mode analysis of conformational transitions in DNA-dependent polymerases: the elastic network model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Mapping the anthrax protective antigen binding site on the lethal and edema factors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Conformational change of proteins arising from normal mode calculations

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Direct evaluation of thermal fluctuations in proteins using a single-parameter harmonic potential

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Anthrax lethal factor (LF) mediated block of the anthrax protective antigen (PA) ion channel: effect of ionic strength and voltage

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Large-scale structural changes accompany binding of lethal factor to anthrax protective antigen: a cryo-electron microscopic study

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Anthrax protective antigen: efficiency of translocation is independent of the number of ligands bound to the prepore

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Flexible multi-scale fitting of atomic structures into low-resolution electron density maps with elastic network normal mode analysis.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Building-block approach for determining low-frequency normal modes of macromolecules.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Quantitative fitting of atomic models into observed densities derived by electron microscopy.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Collective motions in HIV-1 reverse transcriptase: examination of flexibility and enzyme function.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Multi-resolution contour-based fitting of macromolecular structures

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Large Amplitude Elastic Motions in Proteins from a Single-Parameter, Atomic Analysis

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242606

Combining Electron Microscopic with X-Ray Crystallographic Structures

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16943448

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16943448

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1110/PS.062293906

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16943448%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16943448%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

16943448

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16943448%20AND%20SRC:MED&resulttype=core&format=json