The molecular basis of chloroquine block of the inward rectifier Kir2.1 channel (Q36446243)

14 August 2017

The molecular basis of chloroquine block of the inward rectifier Kir2.1 channel (English)

1 reference

Aldo A Rodríguez-Menchaca

14 August 2017

0 references

object named as

Aldo A Rodríguez-Menchaca

0 references

Frank B Sachse

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Ricardo A Navarro-Polanco

1 reference

14 August 2017

Tania Ferrer-Villada

1 reference

14 August 2017

Jason Rupp

1 reference

14 August 2017

Martin Tristani-Firouzi

1 reference

14 August 2017

José A Sánchez-Chapula

1 reference

14 August 2017

language of work or name

English

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publication date

23 January 2008

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Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

1 reference

14 August 2017

105

1 reference

14 August 2017

1 reference

14 August 2017

1364-1368

1 reference

Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4+ T-lymphocytes.

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Randomized dose-ranging controlled trial of AQ-13, a candidate antimalarial, and chloroquine in healthy volunteers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Functional roles of charged amino acid residues on the wall of the cytoplasmic pore of Kir2.1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Mechanism of the voltage sensitivity of IRK1 inward-rectifier K+ channel block by the polyamine spermine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Characterization of inward-rectifier K+ channel inhibition by antiarrhythmic piperazine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Unique Kir2.x properties determine regional and species differences in the cardiac inward rectifier K+ current

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Mechanism of rectification in inward-rectifier K+ channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Molecular dissection of the inward rectifier potassium current (IK1) in rabbit cardiomyocytes: evidence for heteromeric co-assembly of Kir2.1 and Kir2.2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Molecular determinants of voltage-dependent human ether-a-go-go related gene (HERG) K+ channel block

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Kinetics of inward-rectifier K+ channel block by quaternary alkylammonium ions. dimension and properties of the inner pore

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Inward rectifiers in the heart: an update on I(K1).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Ionic Blockage of Sodium Channels in Nerve

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Clinical efficacy of mefloquine in children suffering from chloroquine-resistant Plasmodium falciparum malaria in Nigeria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Inward rectifier potassium channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Evidence for sequential ion-binding loci along the inner pore of the IRK1 inward-rectifier K+ channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Blockade of the inward rectifying potassium current terminates ventricular fibrillation in the guinea pig heart

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Blockade of currents by the antimalarial drug chloroquine in feline ventricular myocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Chloroquine blocks the background potassium current in guinea pig atrial myocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Treatment of acute chloroquine poisoning: a 5-year experience

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

The anomalous rectification and cation selectivity of the membrane of a starfish egg cell.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Treatment of severe chloroquine poisoning

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Antiarrhythmic potential of chloroquine: new use for an old drug.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Localization of PIP2 activation gate in inward rectifier K+ channels

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Gating of inwardly rectifying K+ channels localized to a single negatively charged residue

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

The pharmacokinetics and electrocardiographic effects of chloroquine in healthy subjects.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+ channel

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234144

The electric response at a sensory nerve ending

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18216262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential distribution of Kir2.1 and Kir2.3 subunits in canine atrium and ventricle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18216262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The influence of potassium and chloride ions on the membrane potential of single muscle fibres

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18216262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0708153105

1 reference

14 August 2017

0 references

1 reference

14 August 2017

PubMed publication ID

18216262

1 reference