Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism (Q36421287)

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English	Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism (English)

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Europe PubMed Central

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14 August 2017

arterial hypertension

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1 reference

based on heuristic

inferred from title

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based on heuristic

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author name string

Xinping Chen

1

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Europe PubMed Central

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14 August 2017

Megha Talati

2

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14 August 2017

Joshua P Fessel

3

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Europe PubMed Central

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14 August 2017

Anna R Hemnes

4

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Europe PubMed Central

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14 August 2017

Santhi Gladson

5

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14 August 2017

Jaketa French

6

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14 August 2017

Sheila Shay

7

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14 August 2017

Aaron Trammell

8

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14 August 2017

John A Phillips

9

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14 August 2017

Rizwan Hamid

10

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14 August 2017

Joy D Cogan

11

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14 August 2017

Elliott P Dawson

12

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14 August 2017

Kristie E Womble

13

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14 August 2017

Lora K Hedges

14

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14 August 2017

Elizabeth G Martinez

15

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14 August 2017

Lisa A Wheeler

16

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14 August 2017

James E Loyd

17

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14 August 2017

Susan J Majka

18

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14 August 2017

James West

19

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14 August 2017

Eric D Austin

20

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14 August 2017

language of work or name

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publication date

20 October 2015

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14 August 2017

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133

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14 August 2017

1

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14 August 2017

82-97

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Europe PubMed Central

PMC publication ID

14 August 2017

Hyperinsulinemia Enhances Hepatic Expression of the Fatty Acid Transporter Cd36 and Provokes Hepatosteatosis and Hepatic Insulin Resistance

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MicroRNA expression profiling in PBMCs: a potential diagnostic biomarker of chronic hepatitis C

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A miR-208-Mef2 axis drives the decompensation of right ventricular function in pulmonary hypertension

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The structure, function and evolution of proteins that bind DNA and RNA

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Sex-dependent influence of endogenous estrogen in pulmonary hypertension

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The genetics of pulmonary arterial hypertension

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Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension.

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MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes.

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Interaction between bone morphogenetic protein receptor type 2 and estrogenic compounds in pulmonary arterial hypertension

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Relevant issues in the pathology and pathobiology of pulmonary hypertension

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Mitochondrial dynamics--mitochondrial fission and fusion in human diseases

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Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension.

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MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts

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Beta cell 5'-shifted isomiRs are candidate regulatory hubs in type 2 diabetes

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Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension.

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An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

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Mir-206 regulates pulmonary artery smooth muscle cell proliferation and differentiation

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A potential role for insulin resistance in experimental pulmonary hypertension

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Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming

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Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension

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Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension

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Suppression of microRNA-29 expression by TGF-β1 promotes collagen expression and renal fibrosis

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Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8

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Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.

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TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29

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miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1)

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Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension

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Pulmonary arterial hypertension

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Tissue-specific promoters regulate aromatase cytochrome P450 expression

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Epigenetics: an epigenetic twist on the missing heritability of complex traits

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Identifiers

10.1161/CIRCULATIONAHA.115.016133

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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