EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin (Q36429059)

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English	EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Sharmila Shankar

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Luke Marsh

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Rakesh K Srivastava

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

publication date

13 September 2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

372

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1-2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

83-94

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Influence of IL-8 on the epithelial-mesenchymal transition and the tumor microenvironment

1 reference

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EGCG enhances the therapeutic potential of gemcitabine and CP690550 by inhibiting STAT3 signaling pathway in human pancreatic cancer

1 reference

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Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

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Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications

1 reference

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Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics

1 reference

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30 September 2017

IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells

1 reference

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Hypoxia induces tumor and endothelial cell migration in a Semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor Neuropilin 2

1 reference

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Mechanistic issues concerning cancer prevention by tea catechins

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EGCG, green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment

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Green tea epigallocatechin gallate exhibits anticancer effect in human pancreatic carcinoma cells via the inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor.

1 reference

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Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

1 reference

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Pancreatic cancer: pathobiology, treatment options, and drug delivery

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FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol

1 reference

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Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors.

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Cancer prevention by tea: animal studies, molecular mechanisms and human relevance

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Metastasis: from dissemination to organ-specific colonization

1 reference

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30 September 2017

Neuropilin-2-mediated tumor growth and angiogenesis in pancreatic adenocarcinoma

1 reference

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BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3.

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Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor

1 reference

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Mechanisms of adaptive angiogenesis to tissue hypoxia

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Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer

1 reference

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Metastasis and stem cell pathways

1 reference

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FOXO transcription factors in the regulatory networks of longevity

1 reference

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Epigallocatechin-3-gallate inhibits cell cycle and induces apoptosis in pancreatic cancer

1 reference

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Regulation of angiogenesis by hypoxia-inducible factor 1.

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Promoter characterization of Semaphorin SEMA3F, a tumor suppressor gene

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Innovative agents in cancer prevention.

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Human FOX gene family (Review)

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Pancreatic carcinoma cells express neuropilins and vascular endothelial growth factor, but not vascular endothelial growth factor receptors

1 reference

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Chemopreventive potential of epigallocatechin gallate and genistein: evidence from epidemiological and laboratory studies

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Mechanisms of Cancer Prevention by Tea Constituents

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A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis, G(1) arrest, and regulation of gene expression

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Focus on pancreas cancer

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Surgical and medical therapy for pancreatic carcinoma

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Molecular epidemiology of pancreatic cancer

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Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

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Chemopreventive effects of tea extracts and various components on human pancreatic and prostate tumor cells in vitro

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Epidemiology of and risk factors for pancreatic cancer.

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EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer

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Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer.

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Angiogenesis and proteins of the hemostatic system

1 reference

https://pubmed.ncbi.nlm.nih.gov/22971992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22971992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastasis: Influencing bad behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/22971992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastasis: Route master

1 reference

https://pubmed.ncbi.nlm.nih.gov/22971992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22971992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-012-1448-Y

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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