Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death (Q36412965)

14 August 2017

Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death (English)

1 reference

14 August 2017

0 references

Dario Balestra

0 references

Saverio Marchi

0 references

Paolo Pinton

0 references

Carlotta Giorgi

1 reference

14 August 2017

Giampaolo Morciano

1 reference

14 August 2017

Mirko Pinotti

1 reference

14 August 2017

Daniela Perrone

1 reference

14 August 2017

4 November 2015

1 reference

Molecular Biology of the Cell

14 August 2017

1 reference

14 August 2017

1 reference

14 August 2017

1 reference

14 August 2017

20-34

1 reference

PMC publication ID

4694758

describes a project that uses

14 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4694758/fullTextXML

inferred from PubMed Central ID database lookup

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Sabutoclax (BI97C1) and BI112D1, putative inhibitors of MCL-1, induce mitochondrial fragmentation either upstream of or independent of apoptosis

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Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

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Delving deeper: MCL-1's contributions to normal and cancer biology

30 September 2017

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Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

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Mitochondrial Ca(2+) and apoptosis

30 September 2017

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Splice modulating therapies for human disease

30 September 2017

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Relation between mitochondrial membrane potential and ROS formation.

30 September 2017

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The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites

30 September 2017

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A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy

30 September 2017

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Modulation of biological processes in the nucleus by delivery of DNA oligonucleotides conjugated with gold nanoparticles

30 September 2017

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Mcl-1; the molecular regulation of protein function

30 September 2017

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Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling

30 September 2017

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MCL-1ES, a novel variant of MCL-1, associates with MCL-1L and induces mitochondrial cell death

30 September 2017

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A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase

30 September 2017

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Modification of alternative splicing of Mcl-1 pre-mRNA using antisense morpholino oligonucleotides induces apoptosis in basal cell carcinoma cells

30 September 2017

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Down-regulation of Mcl-1 with antisense technology alters the effect of various cytotoxic agents used in treatment of squamous cell carcinoma of the head and neck.

30 September 2017

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Intravesically administered antisense oligonucleotides targeting heat-shock protein-27 inhibit the growth of non-muscle-invasive bladder cancer

30 September 2017

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Mitochondrial calcium signalling and cell death: approaches for assessing the role of mitochondrial Ca2+ uptake in apoptosis

30 September 2017

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Mcl-1 is a relevant molecular target for antisense oligonucleotide strategies in gastric cancer cells

30 September 2017

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OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

30 September 2017

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Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

30 September 2017

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Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy

30 September 2017

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Promoting apoptosis as a strategy for cancer drug discovery

30 September 2017

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Mcl-1 blocks radiation-induced apoptosis and inhibits clonogenic cell death.

30 September 2017

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The anti-apoptotic protein Mcl-1 inhibits mitochondrial Ca2+ signals

30 September 2017

1 reference

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Antisense therapy for cancer

30 September 2017

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Disruption of fusion results in mitochondrial heterogeneity and dysfunction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis

30 September 2017

1 reference

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Bcl-2-family proteins and the role of mitochondria in apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

hFis1, a novel component of the mammalian mitochondrial fission machinery

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Mammalian dynamin-like protein DLP1 tubulates membranes

30 September 2017

1 reference

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30 September 2017

1 reference

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MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Functional diversity in the dynamin family

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Identification and Subcellular Localization of a Novel Mammalian Dynamin-Related Protein Homologous to Yeast Vps1p and Dnm1p

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Bcl-2 and Bcl-2-Related Proteins in Apoptosis Regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Mechanisms by which mitochondria transport calcium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Identification of PTEN at the ER and MAMs and its regulation of Ca(2+) signaling and apoptosis in a protein phosphatase-dependent manner

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

28 June 2018

SnapShot: BCL-2 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

The Mechanism of Ion Translocation in Mitochondria. 4. Coupling of K+ Efflux with Ca2+ Uptake

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Bcl-2-family proteins: the role of the BH3 domain in apoptosis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694758

Expression of Mcl-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression

21 September 2018

1 reference

12 December 2020

The Initial Velocities of Calcium Uptake by Rat Liver Mitochondria

1 reference

12 December 2020

Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis

1 reference

12 December 2020

Mitochondrial Dynamics in Cell Life and Death

1 reference

12 December 2020

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E15-01-0028

1 reference

14 August 2017

1 reference

PMC publication ID

4694758

14 August 2017

PubMed publication ID

26538029

1 reference

PMC publication ID

4694758