Polymorphisms in the Fc gamma receptor IIIA and Toll-like receptor 9 are associated with protection against severe malarial anemia and changes in circulating gamma interferon levels (Q36396890)

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English	Polymorphisms in the Fc gamma receptor IIIA and Toll-like receptor 9 are associated with protection against severe malarial anemia and changes in circulating gamma interferon levels	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Polymorphisms in the Fc gamma receptor IIIA and Toll-like receptor 9 are associated with protection against severe malarial anemia and changes in circulating gamma interferon levels (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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toll-like receptor

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Winnie A. Okeyo

object named as

Winnie A Okeyo

2

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8

object named as

John Vulule

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

9

object named as

Collins Ouma

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Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Elly O Munde

1

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Europe PubMed Central

PMC publication ID

13 August 2017

Samwel B Anyona

3

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Europe PubMed Central

PMC publication ID

13 August 2017

Evans Raballah

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Stephen Konah

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Wilson Okumu

6

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Europe PubMed Central

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13 August 2017

Lilian Ogonda

7

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Europe PubMed Central

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13 August 2017

language of work or name

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publication date

8 October 2012

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Europe PubMed Central

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13 August 2017

Infection and Immunity

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Europe PubMed Central

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13 August 2017

80

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Europe PubMed Central

PMC publication ID

13 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

4435-4443

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497437

30 September 2017

Identification of inflammatory biomarkers for pediatric malarial anemia severity using novel statistical methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497437

30 September 2017

Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497437

30 September 2017

Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranian malaria patients

1 reference

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Bacteremia in Kenyan Children Presenting with Malaria

1 reference

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30 September 2017

TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria

1 reference

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Fcgamma receptors: structure, function and role as genetic risk factors in SLE

1 reference

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Retention of erythrocytes in the spleen: a double-edged process in human malaria

1 reference

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30 September 2017

Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.

1 reference

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Variants in the toll-like receptor signaling pathway and clinical outcomes of malaria.

1 reference

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30 September 2017

Plasmodium falciparum glycosylphosphatidylinositol toxin interacts with the membrane of non-parasitized red blood cells: a putative mechanism contributing to malaria anemia

1 reference

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Challenges in human genetic diversity: demographic history and adaptation

1 reference

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Relative levels of IL4 and IFN-gamma in complicated malaria: association with IL4 polymorphism and peripheral parasitemia

1 reference

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Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

1 reference

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30 September 2017

Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinical manifestation of malaria during pregnancy

1 reference

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Parasitemia, anemia, and malarial anemia in infants and young children in a rural holoendemic Plasmodium falciparum transmission area

1 reference

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30 September 2017

Pathogen recognition and innate immunity

1 reference

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Bone marrow suppression and severe anaemia associated with persistent plasmodium falciparum infection in african children with microscopically undetectable parasitaemia

1 reference

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Conquering the intolerable burden of malaria: what's new, what's needed: a summary.

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The pathophysiology of falciparum malaria

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FcgammaR polymorphisms: Implications for function, disease susceptibility and immunotherapy.

1 reference

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Genetic analysis of African populations: human evolution and complex disease

1 reference

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Protective effects of the sickle cell gene against malaria morbidity and mortality

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The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection

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Absolute levels and ratios of proinflammatory and anti-inflammatory cytokine production in vitro predict clinical immunity to plasmodium falciparum malaria

1 reference

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Role of Th1 and Th2 cytokines in immune response to uncomplicated Plasmodium falciparum malaria

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30 September 2017

Innate immune recognition

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Factors contributing to anemia after uncomplicated falciparum malaria.

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Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

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Central role of endogenous gamma interferon in protective immunity against blood-stage Plasmodium chabaudi AS infection

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Red cell deformability, splenic function and anaemia in thalassaemia

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Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype

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The molecular dissection of Fc gamma receptor mediated phagocytosis

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Indicators of life-threatening malaria in African children

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Blockade of clearance of immune complexes by an anti-Fc gamma receptor monoclonal antibody

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Cytotoxicity mediated by human Fc receptors for IgG.

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Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation

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Cytokine profiles in children with severe Plasmodium falciparum malaria in an area of unstable malaria transmission in central Sudan

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Increase in NF-kappaB binding affinity of the variant C allele of the toll-like receptor 9 -1237T/C polymorphism is associated with Helicobacter pylori-induced gastric disease

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Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

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Longitudinal cohort study of the epidemiology of malaria infections in an area of intense malaria transmission II. Descriptive epidemiology of malaria infection and disease among children

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IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP2): increasing prevalence with age and association with clinical immunity to malaria.

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Fc receptor biology

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The anaemia of P. falciparum malaria

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Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma.

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28 June 2018

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In-hospital morbidity and mortality due to severe malarial anemia in western Kenya.

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Association of FCgamma receptor IIA (CD32) polymorphism with malarial anemia and high-density parasitemia in infants and young children.

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Absence of association between the Fc gamma receptor IIIA-176F/V polymorphism and the severity of malaria in Thai.

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IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-gamma and TNF-alpha and occurs via a nitric oxide-dependent mechanism

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Development of antimalaria immunity in mice lacking IFN-gamma receptor.

1 reference

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21 September 2018

Mammalian Toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23045477

12 December 2020

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10.1128/IAI.00945-12

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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