Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging (Q36380597)

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English	Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging	scientific article

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15 February 2020

Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging (English)

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15 February 2020

Caenorhabditis elegans

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Werner syndrome

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Alexandra Dallaire

1

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15 February 2020

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Chantal Garand

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15 February 2020

Eric R Paquel

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15 February 2020

Sarah J Mitchell

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15 February 2020

Rafael de Cabo

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15 February 2020

Martin J Simard

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15 February 2020

Michel Lebel

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1 September 2012

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15 February 2020

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15 February 2020

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15 February 2020

9

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15 February 2020

636-647

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15 February 2020

describes a project that uses

object named as

limma

2 references

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3492227

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

MicroRNAs and their roles in aging.

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30 September 2017

An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis

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30 September 2017

Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice

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30 September 2017

The adipokine leptin increases skeletal muscle mass and significantly alters skeletal muscle miRNA expression profile in aged mice

1 reference

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30 September 2017

The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492227

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Novel modulators of senescence, aging, and longevity: Small non-coding RNAs enter the stage.

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30 September 2017

The Caenorhabditis elegans Werner syndrome protein functions upstream of ATR and ATM in response to DNA replication inhibition and double-strand DNA breaks.

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30 September 2017

MicroRNAs in C. elegans Aging: Molecular Insurance for Robustness?

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MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging

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30 September 2017

Vitamin C restores healthy aging in a mouse model for Werner syndrome

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30 September 2017

Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light

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The impact of noncoding RNA on the biochemical and molecular mechanisms of aging

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30 September 2017

Biochemical characterization of the WRN-1 RecQ helicase of Caenorhabditis elegans

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30 September 2017

Old age and the hepatic sinusoid

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30 September 2017

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

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30 September 2017

Most Caenorhabditis elegans microRNAs are individually not essential for development or viability

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30 September 2017

microRNA expression in the aging mouse lung

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30 September 2017

MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines

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30 September 2017

Current advances in unraveling the function of the Werner syndrome protein

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Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

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What can progeroid syndromes tell us about human aging?

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Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice

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30 September 2017

Homologous recombination resolution defect in werner syndrome

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30 September 2017

Characterization of the human and mouse WRN 3'-->5' exonuclease

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30 September 2017

Ku complex interacts with and stimulates the Werner protein

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30 September 2017

The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases

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30 September 2017

The Werner syndrome protein is involved in RNA polymerase II transcription

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30 September 2017

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

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30 September 2017

Biochemical basis of lipofuscin, ceroid, and age pigment-like fluorophores

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30 September 2017

A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility

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Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations

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Resveratrol improves insulin resistance hyperglycemia and hepatosteatosis but not hypertriglyceridemia, inflammation, and life span in a mouse model for Werner syndrome

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Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1

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Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease

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10.18632/AGING.100489

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15 February 2020

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15 February 2020

PubMed publication ID

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15 February 2020

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