B-cell tolerance checkpoints in healthy humans and patients with systemic lupus erythematosus (Q36388680)

13 August 2017

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title

B-cell tolerance checkpoints in healthy humans and patients with systemic lupus erythematosus (English)

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systemic lupus erythematosus

13 August 2017

main subject

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author name string

Sergey Yurasov

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13 August 2017

Johanna Hammersen

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13 August 2017

Thomas Tiller

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13 August 2017

Makoto Tsuiji

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13 August 2017

Hedda Wardemann

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13 August 2017

language of work or name

English

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publication date

1 December 2005

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Annals of the New York Academy of Sciences

13 August 2017

published in

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13 August 2017

volume

1062

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13 August 2017

page(s)

165-174

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Somatic generation of antibody diversity

13 August 2017

cites work

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Predominant autoantibody production by early human B cell precursors

21 January 2018

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RAGs and regulation of autoantibodies

21 January 2018

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Receptor editing: an approach by autoreactive B cells to escape tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1358.019

B lymphocytes may escape tolerance by revising their antigen receptors

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Receptor editing in self-reactive bone marrow B cells

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Surrogate light chain expressing human peripheral B cells produce self-reactive antibodies

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Molecular structure of eight human autoreactive monoclonal antibodies

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Bruton's tyrosine kinase is essential for human B cell tolerance

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Receptor editing occurs frequently during normal B cell development.

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Expression of a targeted lambda 1 light chain gene is developmentally regulated and independent of Ig kappa rearrangements

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells

21 January 2018

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Human autoantibody silencing by immunoglobulin light chains

21 January 2018

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21 January 2018

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21 January 2018

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Delineating the genetic basis of systemic lupus erythematosus

21 January 2018

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Defective B cell tolerance checkpoints in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Use of immunoglobulin variable-region genes by normal subjects and patients with systemic lupus erythematosus

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Immunoglobulin variable-region gene usage in systemic autoimmune diseases

21 January 2018

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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Systemic exposure to irradiated apoptotic cells induces autoantibody production

21 January 2018

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Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

21 January 2018

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TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

21 January 2018

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Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

21 January 2018

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Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

21 January 2018

1 reference

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Challenges in bringing the bench to bedside in drug development for SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Contribution of Receptor Editing to the Antibody Repertoire

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1358.019

21 January 2018

Identifiers

DOI

10.1196/ANNALS.1358.019

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13 August 2017

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