Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice. (Q36367698)

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English	Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice.	scientific article

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21 October 2019

Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice (English)

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21 October 2019

Anthony W. Purcell

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21 October 2019

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21 October 2019

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P Reynolds

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21 October 2019

T P Gordon

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21 October 2019

J McCluskey

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21 October 2019

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1 November 1996

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21 October 2019

Journal of Experimental Medicine

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21 October 2019

184

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21 October 2019

5

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21 October 2019

1857-1870

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21 October 2019

Immunology taught by viruses

1 reference

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30 September 2017

The inability to process a self-peptide allows autoreactive T cells to escape tolerance

1 reference

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30 September 2017

Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands

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30 September 2017

Role of intermolecular/intrastructural B- and T-cell determinants in the diversification of autoantibodies to ribonucleoprotein particles

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30 September 2017

Antigen mimicry in autoimmune disease sharing of amino acid residues critical for pathogenic T cell activation

1 reference

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30 September 2017

Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen

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30 September 2017

Antigen analogs/MHC complexes as specific T cell receptor antagonists

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30 September 2017

Intra- and intermolecular spreading of autoimmunity involving the nuclear self-antigens La (SS-B) and Ro (SS-A).

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30 September 2017

Structure and function of La and Ro RNPs

1 reference

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30 September 2017

Identification of a human-specific epitope in a conserved region of the La/SS-B autoantigen

1 reference

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30 September 2017

Dominance and crypticity of T cell antigenic determinants

1 reference

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30 September 2017

Genetic control of autoimmune diabetes in the NOD mouse

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30 September 2017

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

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30 September 2017

Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity

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30 September 2017

Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid

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30 September 2017

A rapid method for the isolation of functional thymus-derived murine lymphocytes

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30 September 2017

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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30 September 2017

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo

1 reference

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30 September 2017

Fine specificities of autoantibodies directed against the Ro, La, Sm, RNP, and Jo-1 proteins defined by two-dimensional gel electrophoresis and immunoblotting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192903

30 September 2017

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

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30 September 2017

Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology

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30 September 2017

How some T cells escape tolerance induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192903

30 September 2017

Sjögren's syndrome nuclear antigen B (La): cDNA cloning, structural domains, and autoepitopes

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30 September 2017

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus

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30 September 2017

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

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30 September 2017

Ro (SS-A) and La (SS-B) ribonucleoprotein complexes: structure, function and antigenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192903

30 September 2017

Recognition of peptides that are immunopathogenic but cryptic. Mechanisms that allow lymphocytes sensitized against cryptic peptides to initiate pathogenic autoimmune processes.

1 reference

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30 September 2017

Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192903

30 September 2017

Immunogenicity and tolerogenicity of self-major histocompatibility complex peptides

1 reference

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30 September 2017

Molecular cloning and preliminary characterization of a novel cytoplasmic antigen recognized by myasthenia gravis sera

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30 September 2017

Specialization, tolerance, memory, competition, latency, and strife among T cells

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30 September 2017

Definition of a discontinuous immunodominant epitope at the NH2 terminus of the La/SS-B ribonucleoprotein autoantigen

1 reference

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30 September 2017

Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants

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30 September 2017

Monoclonal cytolytic T-cell lines

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30 September 2017

T-cell lines producing antigen-specific suppressor factor

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30 September 2017

A new analysis of allogeneic interactions

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30 September 2017

Two Ro (SS-A) autoantibody responses in systemic lupus erythematosus. Correlation of HLA-DR/DQ specificities with quantitative expression of Ro (SS-A) autoantibody

1 reference

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30 September 2017

Class II-restricted presentation of a hen egg lysozyme determinant derived from endogenous antigen sequestered in the cytoplasm or endoplasmic reticulum of the antigen presenting cells

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28 June 2018

Two better cell lines for making hybridomas expressing specific T cell receptors.

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28 June 2018

Limit of T cell tolerance to self proteins by peptide presentation

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28 June 2018

Pseudoautoimmunity in normal mice: anti-histone antibodies elicited by immunization versus induction during graft-versus-host reaction

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28 June 2018

Vaccination for Disease

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28 June 2018

Mapping of epitopes on the La(SS-B) autoantigen of primary Sjögren's syndrome: identification of a cross-reactive epitope

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28 June 2018

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

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28 June 2018

Characterization of the mouse autoantigen La (SS-B). Identification of conserved RNA-binding motifs, a putative ATP binding site and reactivity of recombinant protein with poly(U) and human autoantibodies

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21 September 2018

Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin

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21 September 2018

Strategies for epitope analysis using peptide synthesis.

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21 September 2018

The T cell repertoire to a multideterminant antigen. Clonal heterogeneity of the T cell response, variation between syngeneic individuals, and in vitro selection of T cell specificities

1 reference

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21 September 2018

Anergic B cells constitutively present self antigen: Enhanced immunoglobulin receptor-mediated presentation of antigenic determinants by B cells is hierarchical

1 reference

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5 December 2018

The immune response to 52-kDa Ro and 60-kDa Ro is linked in experimental autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Responsiveness of autoimmune and normal mice to nucleic acid antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitopes, structural domains, and asymmetry of amino acid residues in SS-B/La nuclear protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell immunity or tolerance as a consequence of self antigen presentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multi-pin peptide synthesis strategy for T cell determinant analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cells that recognize peptide sequences of self MHC class II molecules exist in syngeneic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breaking T cell tolerance with foreign and self co-immunogens. A study of autoimmune B and T cell epitopes of cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Threshold detection of self-antigen/MHC class II complexes formed in vivo: constitutive presentation of an immunodominant epitope of hen egg lysozyme (HEL) in HEL-transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B cells process and present lupus autoantigens that initiate autoimmune T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-peptides in the initiation of lupus autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.184.5.1857

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8920873%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8920873%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8920873%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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