Mechanisms of Disease: ryanodine receptor defects in heart failure and fatal arrhythmia. (Q36359887)

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15 January 2020

review article

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title

Mechanisms of Disease: ryanodine receptor defects in heart failure and fatal arrhythmia (English)

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15 January 2020

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15 January 2020

Masafumi Yano

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15 January 2020

Takeshi Yamamoto

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15 January 2020

Masunori Matsuzaki

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15 January 2020

publication date

1 January 2006

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Nature Clinical Practice Cardiovascular Medicine

15 January 2020

published in

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15 January 2020

volume

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15 January 2020

issue

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15 January 2020

page(s)

43-52

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Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia

15 January 2020

cites work

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Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia

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Serum soluble heat shock protein 60 is elevated in subjects with atherosclerosis in a general population

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Altered intracellular Ca2+ handling in heart failure

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7 January 2021

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor.

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7 January 2021

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

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7 January 2021

Primary structure and functional expression from cDNA of the cardiac ryanodine receptor/calcium release channel

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7 January 2021

Regulation of ryanodine receptors via macromolecular complexes: a novel role for leucine/isoleucine zippers

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7 January 2021

Structure and development of E-C coupling units in skeletal muscle

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7 January 2021

Topology of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum (RyR1).

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7 January 2021

Ryanodine receptors: how many, where and why?

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7 January 2021

Macromolecular complexes regulating cardiac ryanodine receptor function.

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7 January 2021

Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers

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7 January 2021

Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor. Proteins of the cardiac junctional sarcoplasmic reticulum membrane

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7 January 2021

Three-dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum

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7 January 2021

Progression of heart failure: is protein kinase a hyperphosphorylation of the ryanodine receptor a contributing factor?

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7 January 2021

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

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7 January 2021

Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure

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7 January 2021

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

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7 January 2021

Coupled gating between cardiac calcium release channels (ryanodine receptors).

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7 January 2021

Depletion of FKBP does not affect the interaction between isolated ryanodine receptors

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7 January 2021

Defective cardiac ryanodine receptor regulation during atrial fibrillation

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7 January 2021

Characterization of Recombinant Skeletal Muscle (Ser-2843) and Cardiac Muscle (Ser-2809) Ryanodine Receptor Phosphorylation Mutants

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7 January 2021

Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).

1 reference

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7 January 2021

Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.

1 reference

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7 January 2021

Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure

1 reference

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7 January 2021

Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes

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7 January 2021

Rapid adaptation of cardiac ryanodine receptors: modulation by Mg2+ and phosphorylation

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7 January 2021

Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes

1 reference

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7 January 2021

Modulation of excitation-contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger

1 reference

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7 January 2021

Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure.

1 reference

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7 January 2021

Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.

1 reference

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7 January 2021

beta-adrenergic receptor blockers restore cardiac calcium release channel (ryanodine receptor) structure and function in heart failure

1 reference

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7 January 2021

Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1

1 reference

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7 January 2021

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

1 reference

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7 January 2021

Spontaneous diastolic contractions and phosphorylation of the cardiac ryanodine receptor at serine-2808 in congestive heart failure in rat.

1 reference

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7 January 2021

Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure

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7 January 2021

Decrease in myocardial ryanodine receptors and altered excitation-contraction coupling early in the development of heart failure

1 reference

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7 January 2021

Localization of the 12.6-kDa FK506-binding protein (FKBP12.6) binding site to the NH2-terminal domain of the cardiac Ca2+ release channel (ryanodine receptor)

1 reference

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7 January 2021

Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domain

1 reference

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7 January 2021

FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure

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7 January 2021

Ryanodine receptor defects in muscle genetic diseases

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7 January 2021

Ryanodine receptor mutations in malignant hyperthermia and central core disease

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7 January 2021

Arrhythmic disorder mapped to chromosome 1q42-q43 causes malignant polymorphic ventricular tachycardia in structurally normal hearts

1 reference

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7 January 2021

Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak

1 reference

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7 January 2021

RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR)

1 reference

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7 January 2021

Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor.

1 reference

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7 January 2021

Regulation of calcium release by interdomain interaction within ryanodine receptors

1 reference

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7 January 2021

Postulated role of interdomain interaction within the ryanodine receptor in Ca(2+) channel regulation

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Effects of a domain peptide of the ryanodine receptor on Ca2+ release in skinned skeletal muscle fibers

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Interdomain interactions within ryanodine receptors regulate Ca2+ spark frequency in skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Peptide probe study of the critical regulatory domain of the cardiac ryanodine receptor

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Three-dimensional localization of divergent region 3 of the ryanodine receptor to the clamp-shaped structures adjacent to the FKBP binding sites

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Structure of Ca2+ release channel at 14 A resolution

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Defective ryanodine receptor interdomain interactions may contribute to intracellular Ca2+ leak: a novel therapeutic target in heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Direct block of hERG potassium channels by the protein kinase C inhibitor bisindolylmaleimide I (GF109203X).

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Valsartan restores sarcoplasmic reticulum function with no appreciable effect on resting cardiac function in pacing-induced heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

2APB- and JTV519(K201)-sensitive micro Ca2+ waves in arrhythmogenic Purkinje cells that survive in infarcted canine heart.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Effects of a novel cardioprotective drug, JTV-519, on membrane currents of guinea pig ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0419

7 January 2021

Identifiers

DOI

10.1038/NCPCARDIO0419

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16391617%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16391617%20AND%20SRC:MED&resulttype=core&format=json