Molecular aspects of regulation of collagen gene expression in fibrosis. (Q36354729)

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14 January 2020

review article

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title

Molecular aspects of regulation of collagen gene expression in fibrosis (English)

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14 January 2020

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14 January 2020

Rashpal K Bhogal

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14 January 2020

Cristina M Stoica

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14 January 2020

Constantin A Bona

series ordinal

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14 January 2020

publication date

1 November 2005

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Journal of Clinical Immunology

14 January 2020

published in

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14 January 2020

volume

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14 January 2020

issue

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14 January 2020

page(s)

592-603

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Phosphatidylinositol 3-kinase is involved in alpha2(I) collagen gene expression in normal and scleroderma fibroblasts

14 January 2020

cites work

1 reference

Crossref

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Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma

21 January 2018

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Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion

21 January 2018

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Keloid fibroblasts exhibit an altered response to TGF-beta

21 January 2018

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12 December 2020

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

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12 December 2020

Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis

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12 December 2020

Chronic graft-versus-host disease (GVHD) as a model for scleroderma. I. Description of model systems

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12 December 2020

Cutaneous wound healing

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12 December 2020

Structure and biological activity of the extracellular matrix

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12 December 2020

Hereditary emphysema in the tight-skin mouse. Evaluation of pathogenesis

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12 December 2020

Cytokine directed therapy in scleroderma: rationale, current status, and the future

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12 December 2020

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

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12 December 2020

The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.

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12 December 2020

Role of p38 MAPK in Transforming Growth Factor β Stimulation of Collagen Production by Scleroderma and Healthy Dermal Fibroblasts

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12 December 2020

Scleroderma: increased biosynthesis of triple-helical type I and type III procollagens associated with unaltered expression of collagenase by skin fibroblasts in culture

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12 December 2020

Collagens—structure, function, and biosynthesis

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12 December 2020

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts

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12 December 2020

Spontaneous occurrence of anti-fibrillin-1 autoantibodies in tight-skin mice

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12 December 2020

Increased alpha 1(I) procollagen gene expression in tight skin (TSK) mice myocardial fibroblasts is due to a reduced interaction of a negative regulatory sequence with AP-1 transcription factor

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12 December 2020

Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors

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12 December 2020

The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1

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12 December 2020

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster

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12 December 2020

Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation

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12 December 2020

Controlling TGF-beta signaling

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12 December 2020

Overexpression of IL-4 alters the homeostasis in the skin

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12 December 2020

Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4

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12 December 2020

Two different IL-13 receptor chains are expressed in normal human skin fibroblasts, and IL-4 and IL-13 mediate signal transduction through a common pathway

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12 December 2020

Expression of interleukin-4 in scleroderma skin specimens and scleroderma fibroblast cultures. Potential role in fibrosis

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12 December 2020

Autoantibodies in scleroderma and tightskin mice

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12 December 2020

The transforming growth factor-beta system, a complex pattern of cross-reactive ligands and receptors

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12 December 2020

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization

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12 December 2020

TGF-beta signaling from receptors to the nucleus

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12 December 2020

Signal transduction via the interleukin-4 receptor and its correlation with atopy

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12 December 2020

Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts.

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12 December 2020

Control of connective tissue gene expression by TGF beta: role of Smad proteins in fibrosis.

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12 December 2020

IL-4-mediated development of TGF-beta1-producing cells from naïve CD4(+) T cells through a STAT6-independent mechanism

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12 December 2020

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation

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12 December 2020

Structure of the Mutant Fibrillin-1 Gene in the Tight Skin (TSK) Mouse

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12 December 2020

Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma

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12 December 2020

Pathogenesis of fibrosis: type 1 collagen and the skin

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12 December 2020

Transcription factors in lymphocyte development--T and B cells get together

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12 December 2020

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

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12 December 2020

Regulation of immune responses by TGF-beta

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12 December 2020

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

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12 December 2020

Extracellular matrix remodeling by metalloproteinases and plasminogen activators

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12 December 2020

Induction of skin fibrosis in mice expressing a mutated fibrillin-1 gene.

1 reference

12 December 2020

Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.

1 reference

12 December 2020

Elevated serum tumor necrosis factor-alpha levels in patients with systemic sclerosis: association with pulmonary fibrosis

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12 December 2020

Interleukin-13 stimulates the transcription of the human alpha2(I) collagen gene in human dermal fibroblasts

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12 December 2020

TGF-beta signal transduction

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12 December 2020

IL-4 is a differentiation factor for transforming growth factor-beta secreting Th3 cells and oral administration of IL-4 enhances oral tolerance in experimental allergic encephalomyelitis

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12 December 2020

Effect of halofuginone on the development of tight skin (TSK) syndrome

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12 December 2020

Interleukin-1, Interleukin-2, Interleukin-4, Interleukin-6, Tumor Necrosis Factor α, and Interferon-γ Levels in Sera from Patients With Scleroderma

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12 December 2020

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro

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12 December 2020

Interleukin-4 stimulates collagen gene expression in human fibroblast monolayer cultures. Potential role in fibrosis

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12 December 2020

Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts.

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12 December 2020

Interleukin 13 elicits a subset of the activities of its close relative interleukin 4.

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12 December 2020

TGF-beta signaling and the fibrotic response

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12 December 2020

Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts

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12 December 2020

Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts

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12 December 2020

Activated mast cells produce interleukin 13.

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12 December 2020

Inhibition of collagen type I synthesis by skin fibroblasts of graft versus host disease and scleroderma patients: effect of halofuginone

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12 December 2020

Collagenous abnormalities in the heart of the tight-skin mouse

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12 December 2020

Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism.

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12 December 2020

Mouse models for extracellular matrix diseases.

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12 December 2020

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

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12 December 2020

Mouse CD1-specific NK1 T cells: development, specificity, and function

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12 December 2020

Transcriptional control by the TGF-beta/Smad signaling system

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12 December 2020

A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes

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12 December 2020

Mutant fibrillin 1 from tight skin mice increases extracellular matrix incorporation of microfibril-associated glycoprotein 2 and type I collagen

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12 December 2020

Anti-TGF-beta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma

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12 December 2020

Regulation of interleukin-4 on collagen gene expression by systemic sclerosis fibroblasts in culture

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12 December 2020

Collagen matrices attenuate the collagen-synthetic response of cultured fibroblasts to TGF-beta

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12 December 2020

IL-13 effector functions

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12 December 2020

Increased Expression of TGF-β Receptors by Scleroderma Fibroblasts: Evidence for Contribution of Autocrine TGF-β Signaling to Scleroderma Phenotype

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12 December 2020

Genetic and immunologic features associated with scleroderma-like syndrome of TSK mice

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12 December 2020

Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts

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12 December 2020

Specificity, diversity, and regulation in TGF-beta superfamily signaling.

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12 December 2020

Role of profibrogenic cytokines secreted by T cells in fibrotic processes in scleroderma

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12 December 2020

Interleukin-4: a prototypic immunoregulatory lymphokine

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12 December 2020

Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton

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12 December 2020

10.1007/S10875-005-7827-3

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14 January 2020

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24 November 2022

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