Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma (Q36335846)

13 August 2017

Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma (English)

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13 August 2017

Gabriela Chiosis

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Leandro Cerchietti

object named as

Leandro Cerchietti

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Kojo Elenitoba-Johnson

object named as

Kojo Elenitoba-Johnson

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Rebecca L Goldstein

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13 August 2017

Shao Ning Yang

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13 August 2017

Tony Taldone

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13 August 2017

Betty Chang

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13 August 2017

John Gerecitano

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13 August 2017

Rita Shaknovich

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13 August 2017

Wayne Tam

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13 August 2017

John P Leonard

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13 August 2017

Ari Melnick

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13 August 2017

language of work or name

English

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publication date

3 November 2015

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Journal of Clinical Investigation

13 August 2017

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13 August 2017

125

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13 August 2017

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13 August 2017

4559-4571

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describes a project that uses

13 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4665772/fullTextXML

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inferred from PubMed Central ID database lookup

cites work

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells

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Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors

30 September 2017

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PU-H71 effectively induces degradation of IκB kinase β in the presence of TNF-α.

30 September 2017

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Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies

30 September 2017

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SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas

30 September 2017

1 reference

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Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

30 September 2017

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Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

30 September 2017

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A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas

30 September 2017

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Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

30 September 2017

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Displacement affinity chromatography of protein phosphatase one (PP1) complexes

30 September 2017

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STRING 8--a global view on proteins and their functional interactions in 630 organisms

30 September 2017

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Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia

30 September 2017

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SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma

30 September 2017

1 reference

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Cholesterol reporter molecules

30 September 2017

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A guided tour into subcellular colocalization analysis in light microscopy

30 September 2017

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Src-family kinases in B-cell development and signaling

30 September 2017

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Regulation of the Src family kinase Lck by Hsp90 and ubiquitination

30 September 2017

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Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

30 September 2017

1 reference

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A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma

30 September 2017

1 reference

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The role of Hsp90N, a new member of the Hsp90 family, in signal transduction and neoplastic transformation

30 September 2017

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Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signaling

30 September 2017

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Hsp90 is essential for the synthesis and subsequent membrane association, but not the maintenance, of the Src-kinase p56(lck).

30 September 2017

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

30 September 2017

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Membrane cholesterol content accounts for developmental differences in surface B cell receptor compartmentalization and signaling

30 September 2017

1 reference

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CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma

22 September 2018

1 reference

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22 September 2018

Identifiers

DOI

10.1172/JCI80714

1 reference

13 August 2017

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13 August 2017

PubMed publication ID

26529251

1 reference