Transgenic Gαq overexpression induces cardiac contractile failure in mice (Q36302328)

13 August 2017

Transgenic Galphaq overexpression induces cardiac contractile failure in mice (English)

1 reference

PMC publication ID

21567

13 August 2017

Transgenic Gαq overexpression induces cardiac contractile failure in mice (English)

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.94.15.8121

7 November 2024

1 reference

D. D. D'Angelo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9223325

7 November 2024

Y. Sakata

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7 November 2024

J. N. Lorenz

1 reference

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7 November 2024

G. P. Boivin

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7 November 2024

R. A. Walsh

1 reference

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7 November 2024

S. B. Liggett

1 reference

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7 November 2024

G. W. Dorn

1 reference

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7 November 2024

language of work or name

English

0 references

publication date

1 July 1997

1 reference

PMC publication ID

21567

13 August 2017

22 July 1997

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9223325

7 November 2024

number of pages

1 reference

full work available at URL

inferred from page(s)

https://europepmc.org/articles/pmc21567?pdf=render

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Portable Document Format

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open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9223325

https://europepmc.org/articles/PMC21567

7 November 2024

1 reference

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https://europepmc.org/articles/PMC21567?pdf=render

7 November 2024

file format

Portable Document Format

online access status

open access

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1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9223325

https://pnas.org/doi/pdf/10.1073/pnas.94.15.8121

7 November 2024

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Crossref

https://api.crossref.org/works/10.1073/PNAS.94.15.8121

Proceedings of the National Academy of Sciences of the United States of America

7 November 2024

published in

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13 August 2017

1 reference

13 August 2017

1 reference

13 August 2017

8121-8126

1 reference

Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

A mouse model of familial hypertrophic cardiomyopathy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Protein kinase C isoenzymes: divergence in signal transduction?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-epsilon is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Signal transduction via the MAP kinases: proceed at your own RSK.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Molecular and physiological alterations in murine ventricular dysfunction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

In vitro assays of protein kinase C activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Epitope-tagged Gq alpha subunits: expression of GTPase-deficient alpha subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M1 muscarinic acetylcholine rece

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Turnover of Inositol Phospholipids and Signal Transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Studies and perspectives of protein kinase C.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Induction of the skeletal alpha-actin gene in alpha 1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

The cardiac beta-myosin heavy chain isogene is induced selectively in alpha 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Differential changes in cardiac phospholamban and sarcoplasmic reticular Ca(2+)-ATPase protein levels. Effects on Ca2+ transport and mechanics in compensated pressure-overload hypertrophy and congestive heart failure

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21567

Phorbol ester stimulation of protein kinase C activity and ribosomal DNA transcription. Role in hypertrophic growth of cultured cardiomyocytes

22 September 2018

1 reference

12 December 2020

Dissociation of the contractile and hypertrophic effects of vasoconstrictor prostanoids in vascular smooth muscle

1 reference

12 December 2020

Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium

1 reference

12 December 2020

Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy

1 reference

12 December 2020

Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart

1 reference

12 December 2020

Myosin heavy chain regulation and myocyte contractile depression after LV hypertrophy in aortic-banded mice

1 reference

12 December 2020

Dissociation of vasoconstrictor-stimulated basic fibroblast growth factor expression from hypertrophic growth in cultured vascular smooth muscle cells. Relevant roles of protein kinase C

1 reference

12 December 2020

Increased protein kinase C and isozyme redistribution in pressure-overload cardiac hypertrophy in the rat

1 reference

12 December 2020

Regulation of mitogen-activated protein kinase cascade in adult rat heart preparations in vitro

1 reference

12 December 2020

Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling

1 reference

12 December 2020

Angiotensin II–Induced Growth Responses in Isolated Adult Rat Hearts

1 reference

12 December 2020

Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation

1 reference

12 December 2020

In Vivo Echocardiographic Detection of Enhanced Left Ventricular Function in Gene-Targeted Mice With Phospholamban Deficiency

1 reference

12 December 2020

The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular Cardiomyocytes

1 reference

12 December 2020

Prostaglandin F2 alpha stimulates hypertrophic growth of cultured neonatal rat ventricular myocytes

1 reference

12 December 2020

American Journal of Physiology

267

H400

Dorn G W, II

1994

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.94.15.8121

7 November 2024

Identifiers

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dop2yzxwbje4nmj6mi76ovauam

30 July 2022

release_dop2yzxwbje4nmj6mi76ovauam

ADS bibcode

1997PNAS...94.8121D

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dop2yzxwbje4nmj6mi76ovauam

30 July 2022

https://api.fatcat.wiki/v0/release/dop2yzxwbje4nmj6mi76ovauam

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/dop2yzxwbje4nmj6mi76ovauam

1 reference

30 July 2022