ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment (Q36301027)

19 May 2018

title

ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment (English)

1 reference

19 May 2018

Bruce J Tromberg

1 reference

19 May 2018

Tatiana B Krasieva

1 reference

19 May 2018

Chi-Fen Chen

Chi-Fen Chen

1 reference

19 May 2018

Priya Vasudeva

Priya Vasudeva

1 reference

19 May 2018

Francisco Arellano-Espitia

Francisco Espitia

1 reference

19 May 2018

Sebastien de Feraudy

Sebastien de Feraudy

1 reference

19 May 2018

Dave S. Hoon

Dave S Hoon

1 reference

19 May 2018

Anand Ganesan

Anand K Ganesan

1 reference

19 May 2018

author name string

Rolando Ruiz-Vega

1 reference

19 May 2018

Sharon Huang

1 reference

19 May 2018

Chad P Garner

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19 May 2018

Jie Wu

1 reference

19 May 2018

publication date

1 March 2017

1 reference

19 May 2018

published in

Cell Reports

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19 May 2018

volume

1 reference

19 May 2018

issue

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19 May 2018

page(s)

2331-2342

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19 May 2018

The Complexity of the ERK/MAP-Kinase Pathway and the Treatment of Melanoma Skin Cancer

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Beyond Red Hair and Sunburns: Uncovering the Molecular Mechanisms of MC1R Signaling and Repair of UV-Induced DNA Damage

29 June 2018

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Update in genetic susceptibility in melanoma

29 June 2018

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Current State of Animal (Mouse) Modeling in Melanoma Research

29 June 2018

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Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

29 June 2018

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Cancer immunotherapy: harnessing the immune system to battle cancer

29 June 2018

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DNA damage control: regulation and functions of checkpoint kinase 1

29 June 2018

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Efficacy and Safety of Nivolumab in Patients With BRAF V600 Mutant and BRAF Wild-Type Advanced Melanoma: A Pooled Analysis of 4 Clinical Trials

29 June 2018

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Defining the Contribution of MC1R Physiological Ligands to ATR Phosphorylation at Ser435, a Predictor of DNA Repair in Melanocytes

29 June 2018

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Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin

29 June 2018

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BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth

29 June 2018

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PD-1 blockade induces responses by inhibiting adaptive immune resistance

29 June 2018

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Genetic basis for clinical response to CTLA-4 blockade in melanoma

29 June 2018

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PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.

29 June 2018

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Distinguishing between benign and malignant melanocytic nevi by in vivo multiphoton microscopy

29 June 2018

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The M1 and M2 paradigm of macrophage activation: time for reassessment

29 June 2018

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DNA damage sensing by the ATM and ATR kinases.

29 June 2018

1 reference

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Tumor associated macrophages and neutrophils in cancer

29 June 2018

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Meeting report: The future of preclinical mouse models in melanoma treatment is now.

29 June 2018

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A landscape of driver mutations in melanoma

29 June 2018

1 reference

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A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines

29 June 2018

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Germline mutation in ATR in autosomal- dominant oropharyngeal cancer syndrome.

29 June 2018

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Butyrophilins: an emerging family of immune regulators

29 June 2018

1 reference

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Protective and pathogenic functions of macrophage subsets

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Skint-1 is a highly specific, unique selecting component for epidermal T cells

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Detection of M2-macrophages in uveal melanoma and relation with survival.

29 June 2018

1 reference

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Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.

29 June 2018

1 reference

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Oncogenic Braf induces melanocyte senescence and melanoma in mice

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

The role of p53 in pigmentation, tanning and melanoma

29 June 2018

1 reference

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ATR: an essential regulator of genome integrity

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Deciphering AP-1 function in tumorigenesis: fra-ternizing on target promoters

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Genetics of melanoma predisposition

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

ATR and ATRIP: partners in checkpoint signaling

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

ATR disruption leads to chromosomal fragmentation and early embryonic lethality

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Chk1 is essential for the development of murine epidermal melanocytes

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

ATR and H2AX cooperate in maintaining genome stability under replication stress

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5393360

Dendritic cell and macrophage infiltration in microsatellite-unstable and microsatellite-stable colorectal cancer

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28273450

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28273450

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2017.02.040

1 reference

19 May 2018

PMC publication ID

5393360

1 reference

19 May 2018

PubMed publication ID

28273450

1 reference

19 May 2018