Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex (Q36292698)

13 August 2017

Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex (English)

1 reference

13 August 2017

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14 June 2020

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14 June 2020

Michael G Natchus

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14 June 2020

Marco Weisshaar

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14 June 2020

Shuli Mao

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14 June 2020

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author name string

Alberto Jiménez-Somarribas

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14 June 2020

Jeong-Joong Yoon

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14 June 2020

Robert M Cox

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14 June 2020

Jose R Marengo

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14 June 2020

Deborah G Mitchell

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14 June 2020

Zachary P Morehouse

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14 June 2020

Dan Yan

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14 June 2020

Ivan Solis

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14 June 2020

language of work or name

English

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publication date

28 February 2017

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Journal of Medicinal Chemistry

13 August 2017

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14 June 2020

volume

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14 June 2020

issue

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14 June 2020

page(s)

2305-2325

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Taxonomy of the order Mononegavirales: update 2016

14 June 2020

cites work

1 reference

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Structure-guided design of small-molecule therapeutics against RSV disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Molecular mechanism of respiratory syncytial virus fusion inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Tunable and reversible drug control of protein production via a self-excising degron.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis

30 September 2017

1 reference

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Cross-resistance mechanism of respiratory syncytial virus against structurally diverse entry inhibitors

30 September 2017

1 reference

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A novel series of histamine H4 receptor antagonists based on the pyrido[3,2-d]pyrimidine scaffold: comparison of hERG binding and target residence time with PF-3893787.

30 September 2017

1 reference

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Structure-based discovery of cellular-active allosteric inhibitors of FAK

30 September 2017

1 reference

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A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis

30 September 2017

1 reference

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MScreen: an integrated compound management and high-throughput screening data storage and analysis system.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Respiratory syncytial virus load, viral dynamics, and disease severity in previously healthy naturally infected children

30 September 2017

1 reference

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Viral load drives disease in humans experimentally infected with respiratory syncytial virus

30 September 2017

1 reference

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A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Influenza and respiratory syncytial virus in the elderly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern

30 September 2017

1 reference

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Improved statistical methods for hit selection in high-throughput screening

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Mortality associated with influenza and respiratory syncytial virus in the United States

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Respiratory syncytial virus infection: immune response, immunopathogenesis, and treatment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Pathogenesis and treatment of bronchiolitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Pathological changes in virus infections of the lower respiratory tract in children

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Association between respiratory syncytial virus outbreaks and lower respiratory tract deaths of infants and young children

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Early ribavirin treatment of respiratory syncytial viral infection in high-risk children

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Discovery of 4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine (ALS-8176), a first-in-class RSV polymerase inhibitor for treatment of human respiratory syncytial virus infection

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

AutoGPA: An Automated 3D-QSAR Method Based on Pharmacophore Alignment and Grid Potential Analysis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Oral GS-5806 activity in a respiratory syncytial virus challenge study.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Exploration of ring size in a series of cyclic vicinal diamines with σ₁ receptor affinity.

22 September 2018

1 reference

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Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Asymmetric total syntheses of (-)-jorumycin, (-)-renieramycin G, 3-epi-jorumycin, and 3-epi-renieramycin G.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5504085

Histone deacetylase inhibitors derived from 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine and related heterocycles selective for the HDAC6 isoform

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28245119

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ACS.JMEDCHEM.6B01568

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14 June 2020

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14 June 2020

PubMed publication ID

28245119

1 reference

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