Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage (Q36294511)

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English	Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

0 references

author name string

Snigdha Gaur

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Joyce E Heckman

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

John M Burke

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

12 November 2007

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

14

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

55-65

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Dissecting the multistep reaction pathway of an RNA enzyme by single-molecule kinetic "fingerprinting".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Satellite tobacco ringspot virus RNA: A subset of the RNA sequence is sufficient for autolytic processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Water in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Folding and catalysis of the hairpin ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Inhibition of viral replication by ribozyme: mutational analysis of the site and mechanism of antiviral activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

In vitro selection of second site revertants analysis of the hairpin ribozyme active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Transition state stabilization by a catalytic RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Functional involvement of G8 in the hairpin ribozyme cleavage mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Investigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Structure and function of the hairpin ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Structural basis for heterogeneous kinetics: reengineering the hairpin ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Tertiary structure formation in the hairpin ribozyme monitored by fluorescence resonance energy transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Reconstitution of hairpin ribozyme activity following separation of functional domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Essential nucleotide sequences and secondary structure elements of the hairpin ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Mutagenesis of the hairpin ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

An improved version of the hairpin ribozyme functions as a ribonucleoprotein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

RNA catalytic properties of the minimum (-)sTRSV sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Autolytic processing of a phosphorothioate diester bond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

Nucleotide sequence and newly formed phosphodiester bond of spontaneously ligated satellite tobacco ringspot virus RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

'Hairpin' catalytic RNA model: evidence for helices and sequence requirement for substrate RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

30 September 2017

The folding of the hairpin ribozyme: dependence on the loops and the junction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

29 June 2018

Tertiary structure stabilization promotes hairpin ribozyme ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

29 June 2018

Nucleotide analog interference mapping of the hairpin ribozyme: implications for secondary and tertiary structure formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

29 June 2018

RNA mediated formation of a phosphorothioate diester bond.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

29 June 2018

Role of an active site guanine in hairpin ribozyme catalysis probed by exogenous nucleobase rescue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

22 September 2018

Solvent Protection of the Hammerhead Ribozyme in the Ground State: Evidence for a Cation-Assisted Conformational Change Leading to Catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

22 September 2018

Tertiary structure stability of the hairpin ribozyme in its natural and minimal forms: different energetic contributions from a ribose zipper motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

22 September 2018

A base change in the catalytic core of the hairpin ribozyme perturbs function but not domain docking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

22 September 2018

Stability of hairpin ribozyme tertiary structure is governed by the interdomain junction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

22 September 2018

Kinetics and thermodynamics of intermolecular catalysis by hairpin ribozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151026

22 September 2018

Structural basis for the guanosine requirement of the hairpin ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conformational change in the "loop E-like" motif of the hairpin ribozyme is coincidental with domain docking and is essential for catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic and structural assays for the hairpin ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Solvent Dynamics in Stabilizing the Transition State of RNA Hydrolysis by Hairpin Ribozyme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purine functional groups in essential residues of the hairpin ribozyme required for catalytic cleavage of RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Four ribose 2'-hydroxyl groups essential for catalytic function of the hairpin ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-mapping of the hairpin ribozyme. Magnesium-dependent folding and evidence for tertiary interactions within the ribozyme-substrate complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic mechanism of the hairpin ribozyme. Identification and characterization of two nonexchangeable conformations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An unusual pH-independent and metal-ion-independent mechanism for hairpin ribozyme catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational Analysis of Loops 1 and 5 of the Hairpin Ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The solvent-protected core of the hairpin ribozyme-substrate complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17998292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1261/RNA.716108

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

0 references

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