Inhibitors of proprotein convertases (Q36282129)

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English	Inhibitors of proprotein convertases	scientific article

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instance of

scholarly article

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Europe PubMed Central

PubMed publication ID

16215768

retrieved

13 August 2017

review article

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Europe PubMed Central

title

Inhibitors of proprotein convertases (English)

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Europe PubMed Central

PubMed publication ID

16215768

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13 August 2017

author name string

Ajoy Basak

series ordinal

1

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stated in

Europe PubMed Central

PubMed publication ID

16215768

retrieved

13 August 2017

publication date

8 October 2005

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stated in

Europe PubMed Central

PubMed publication ID

16215768

retrieved

13 August 2017

published in

Journal of Molecular Medicine

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Europe PubMed Central

PubMed publication ID

16215768

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13 August 2017

volume

83

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stated in

Europe PubMed Central

PubMed publication ID

16215768

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13 August 2017

issue

11

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Europe PubMed Central

PubMed publication ID

16215768

retrieved

13 August 2017

page(s)

844-855

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Europe PubMed Central

PubMed publication ID

16215768

retrieved

13 August 2017

cites work

Localization of endogenous furin in cultured cell lines

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21 January 2018

Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy

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21 January 2018

Inhibitory Effect of the .ALPHA.1-Antitrypsin Pittsburgh Type-Mutant(.ALPHA.1-PIM/R) on Proinsulin Processing in the Regulated Secretory Pathway of the Pancreatic .BETA.-Cell Line MIN6

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21 January 2018

Enzymic characterization of murine and human prohormone convertase-1 (mPC1 and hPC1) expressed in mammalian GH4C1 cells

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21 January 2018

Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered α2-macroglobulin containing a furin recognition sequence in the bait region

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21 January 2018

Effects of L- and D-REKR amino acid-containing peptides on HIV and SIV envelope glycoprotein precursor maturation and HIV and SIV replication

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reference URL

https://api.crossref.org/works/10.1007%2FS00109-005-0710-0

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21 January 2018

Inhibitors of the subtilase-like pro-protein convertases (SPCs).

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arg15-Lys17-Arg18 turkey ovomucoid third domain inhibits human furin.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folding pathway mediated by an intramolecular chaperone. The inhibitory and chaperone functions of the subtilisin propeptide are not obligatorily linked

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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Engineered eglin c variants inhibit yeast and human proprotein processing proteases, Kex2 and furin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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The association of cardiovascular disease risk factors with abdominal obesity in Canada. Canadian Heart Health Surveys Research Group

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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The peptidase zymogen proregions: nature's way of preventing undesired activation and proteolysis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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Obesity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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Isolation, purification, and characterization of gamma-lipotropic hormone from sheep pituitary glands

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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The proprotein convertases

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM)

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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Proprotein convertase PC1/3-related peptides are potent slow tight-binding inhibitors of murine PC1/3 and Hfurin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Furin inhibition by compounds of copper and zinc

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Proprotein convertases and the pathophysiology of human diseases: prospective considerations

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

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Active site binding loop stabilization in the subtilisin inhibitor eglin c: structural and functional studies on specifically designed mutants in complex with subtilisin and the uncomplexed inhibitor

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Proprotein convertases are important mediators of the adipocyte differentiation of mouse 3T3-L1 cells.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Synthetic peptides derived from the prosegments of proprotein convertase 1/3 and furin are potent inhibitors of both enzymes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Barley serine proteinase inhibitor 2-derived cyclic peptides as potent and selective inhibitors of convertases PC1/3 and furin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of tight binding inhibitors and their action on the proprotein-processing enzyme furin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Inhibition of matrix metalloproteinase 2 maturation and HT1080 invasiveness by a synthetic furin inhibitor

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Toward an enzyme/prodrug strategy for cancer gene therapy: endogenous activation of carboxypeptidase A mutants by the PACE/Furin family of propeptidases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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The pathogenesis and management of painful diabetic neuropathy: a review

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Insulin biosynthesis: evidence for a precursor

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Secreted site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteins

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyarginines are potent furin inhibitors

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidyl substrates containing unnatural amino acid at the P'1 position are potent inhibitors of prohormone convertases

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of convertase-related processing of proendothelin-1

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of pro-IGF-II processing by proprotein convertase 4 in human placental development

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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The posttranslational phase of gene expression: new possibilities in molecular diagnosis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function analysis of the 7B2 CT peptide

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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The prohormone processing enzyme PC3 is a lipid raft-associated transmembrane protein

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

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Modulating furin activity with designed mini-PDX peptides: synthesis and in vitro kinetic evaluation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of furin-like enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEROPS: the peptidase database

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroendocrine secretory protein 7B2: structure, expression and functions

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Enzymic characterization in vitro of recombinant proprotein convertase PC4.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Design and synthesis of novel inhibitors of prohormone convertases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Protease inhibitors formed in situ from copper and tridentate chelates: a generalized approach towards metal-based pharmaceuticals

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Nucleotide sequence of cDNA encoding human alpha 2-macroglobulin and assignment of the chromosomal locus

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histidine‐rich human salivary peptides are inhibitors of proprotein convertases furin and PC7 but act as substrates for PC1

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of soluble recombinant furin by human proteinase inhibitor 8

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Drug delivery of antisense molecules to the brain for treatment of Alzheimer's disease and cerebral AIDS.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of Narc 1, a novel proteinase related to proteinase K

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Structure-function analysis of the prosegment of the proprotein convertase PC5A.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16215768

retrieved

12 December 2020

based on heuristic

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Posttranslational modification of therapeutic proteins in plants

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https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Fluorescent Peptidyl Substrates as an Aid in Studying the Substrate Specificity of Human Prohormone Convertase PC1 and Human Furin and Designing a Potent Irreversible Inhibitor

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Post-translational protein modification as the substrate for long-lasting memory

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16215768

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12 December 2020

based on heuristic

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Identifiers

DOI

10.1007/S00109-005-0710-0

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16215768

retrieved

13 August 2017

PubMed publication ID

16215768

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16215768

retrieved

13 August 2017

 

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